Hostile bile limits anti-cancer immunity

被引：1
|
作者：
Parathan, Pavitha [1 ,2 ,3 ]
Mielke, Lisa A. [1 ,2 ,3 ]
机构：
[1] Olivia Newton John Canc Res Inst, Heidelberg, Vic, Australia
[2] La Trobe Univ, Sch Canc Med, Heidelberg, Vic, Australia
[3] La Trobe Univ, La Trobe Inst Mol Sci, Bundoora, Vic, Australia
来源：
IMMUNITY | 2024年 / 57卷 / 04期
关键词：
D O I：
10.1016/j.immuni.2024.03.006
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Various microbial metabolites promote cell transformation. In this issue of Immunity , Cong et al. show that deoxycholic acid (DCA), a microbial metabolite of bile, promotes tumor growth by suppressing antitumor CD8 + T cell responses via dysregulation of calcium efflux.
引用
收藏
页码：834 / 836
页数：3
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