Advances in Nanocarriers for Anticancer Drugs Delivery

被引：70

作者：

Ali, Imran ^{[1
,2
]}

Lone, Mohammad Nadeem ^{[1
]}

Suhail, Mohammad ^{[1
]}

Mukhtar, Sofi Danish ^{[1
]}

Asnin, Leonid ^{[2
]}

机构：

[1] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India

[2] Perm Natl Res Polytech Univ, Perm, Russia

来源：

CURRENT MEDICINAL CHEMISTRY | 2016年 / 23卷 / 20期

关键词：

Current challenges; Future prospective; Mechanisms of action; Nano-anticancer drugs; Nanocarriers; Recent advances; TUMOR-TARGETED DELIVERY; MESOPOROUS SILICA NANOPARTICLES; ENHANCED ANTITUMOR EFFICACY; IN-VIVO EVALUATION; CARBON NANOTUBES; CONTROLLED-RELEASE; CANCER-THERAPY; CHITOSAN NANOPARTICLES; POLYMERIC NANOPARTICLES; CELLULAR UPTAKE;

D O I：

10.2174/0929867323666160405111152

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cancer is the most dangerous disease to haunt the mankind in the world today. Generally, the overall cancer mortality rates are similar in both the sexes. The reasons for most of these deaths are inefficacy and failure of the current methods of treatments or the unavailability of treatment options. The researchers of the world are actively integrating nanotechnology of treating of various cancers. The development of smart nanocarriers is one of the most important innovations in this direction. The nanocarriers of the different materials are being developed to improve the efficacy of current treatments. The present article describes the role of nanotechnology in cancer treatment emphasizing cancer nanotherapy, nanocarriers for drug delivery, types and the mechanisms of the nanocarriers. Besides, the efforts are made to discuss the recent advances in the nanocarriers, current challenges and the future prospective.

引用

页码：2159 / 2187

页数：29

共 207 条

[71] Modulation of Induced Cytotoxicity of Doxorubicin by Using Apoferritin and Liposomal Cages [J].

Gumulec, Jaromir ;

Fojtu, Michaela ;

Raudenska, Martina ;

Sztalmachova, Marketa ;

Skotakova, Anna ;

Vlachova, Jana ;

Skalickova, Sylvie ;

Nejdl, Lukas ;

Kopel, Pavel ;

Knopfova, Lucia ;

Adam, Vojtech ;

Kizek, Rene ;

Stiborova, Marie ;

Babula, Petr ;

Masarik, Michal .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (12) :22960-22977

[72] Nanoparticles for drug delivery in cancer treatment [J].

Haley, Barbara ;

Frenkel, Eugene .

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2008, 26 (01) :57-64

[73] The potential of liposorne-encapsulated ciprofloxacin as a tularemia therapy [J].

Hamblin, Karleigh A. ;

Wong, Jonathan P. ;

Blanchard, James D. ;

Atkins, Helen S. .

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2014, 4

[74] Carbon nanotubes filled with a chemotherapeutic agent:: a nanocarrier mediates inhibition of tumor cell growth [J].

Hampel, Silke ;

Kunze, Doreen ;

Haase, Diana ;

Kraemer, Kai ;

Rauschenbach, Mandy ;

Ritscbel, Manfred ;

Leonbardt, Albrecht ;

Thomas, Juergen ;

Oswald, Steffen ;

Hoffmann, Volker ;

Buechner, Bernd .

NANOMEDICINE, 2008, 3 (02) :175-182

[75] Dendrimer-based multilayer nanocarrier for potential synergistic paclitaxel-doxorubicin combination drug delivery [J].

He, Hai ;

Wang, Yao ;

Wen, Hao ;

Jia, Xinru .

RSC ADVANCES, 2014, 4 (07) :3643-3652

[76] Disterolphospholipids: Nonexchangeable Lipids and Their Application to Liposomal Drug Delivery [J].

Huang, Zhaohua ;

Jaafari, Mahmoud Reza ;

Szoka, Francis C., Jr. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (23) :4146-4149

[77] Novel hyaluronic acid (HA) coated drug carriers (HCDCs) for human breast cancer treatment [J].

Hyung, Woochan ;

Ko, Hyunjoo ;

Park, Joseph ;

Lim, Eunkyung ;

Park, Sun Bae ;

Park, Young-Joon ;

Yoon, Ho Geun ;

Suh, Jin Suck ;

Haam, Seungjoo ;

Huh, Yong-Min .

BIOTECHNOLOGY AND BIOENGINEERING, 2008, 99 (02) :442-454

[78] SINGLE-SHELL CARBON NANOTUBES OF 1-NM DIAMETER [J].

IIJIMA, S ;

ICHIHASHI, T .

NATURE, 1993, 363 (6430) :603-605

[79] HELICAL MICROTUBULES OF GRAPHITIC CARBON [J].

IIJIMA, S .

NATURE, 1991, 354 (6348) :56-58

[80] Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer [J].

Inoue, Satoshi ;

Patil, Rameshwar ;

Portilla-Arias, Jose ;

Ding, Hui ;

Konda, Bindu ;

Espinoza, Andres ;

Mongayt, Dmitriy ;

Markman, Janet L. ;

Elramsisy, Adam ;

Phillips, H. Westley ;

Black, Keith L. ;

Holler, Eggehard ;

Ljubimova, Julia Y. .

PLOS ONE, 2012, 7 (02)

← 3 4 5 6 7 8 9 10 11 12 →