Advances in Nanocarriers for Anticancer Drugs Delivery

被引:67
作者
Ali, Imran [1 ,2 ]
Lone, Mohammad Nadeem [1 ]
Suhail, Mohammad [1 ]
Mukhtar, Sofi Danish [1 ]
Asnin, Leonid [2 ]
机构
[1] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India
[2] Perm Natl Res Polytech Univ, Perm, Russia
关键词
Current challenges; Future prospective; Mechanisms of action; Nano-anticancer drugs; Nanocarriers; Recent advances; TUMOR-TARGETED DELIVERY; MESOPOROUS SILICA NANOPARTICLES; ENHANCED ANTITUMOR EFFICACY; IN-VIVO EVALUATION; CARBON NANOTUBES; CONTROLLED-RELEASE; CANCER-THERAPY; CHITOSAN NANOPARTICLES; POLYMERIC NANOPARTICLES; CELLULAR UPTAKE;
D O I
10.2174/0929867323666160405111152
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cancer is the most dangerous disease to haunt the mankind in the world today. Generally, the overall cancer mortality rates are similar in both the sexes. The reasons for most of these deaths are inefficacy and failure of the current methods of treatments or the unavailability of treatment options. The researchers of the world are actively integrating nanotechnology of treating of various cancers. The development of smart nanocarriers is one of the most important innovations in this direction. The nanocarriers of the different materials are being developed to improve the efficacy of current treatments. The present article describes the role of nanotechnology in cancer treatment emphasizing cancer nanotherapy, nanocarriers for drug delivery, types and the mechanisms of the nanocarriers. Besides, the efforts are made to discuss the recent advances in the nanocarriers, current challenges and the future prospective.
引用
收藏
页码:2159 / 2187
页数:29
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