A Case of Vitamin K Deficiency Bleeding in a Newborn: Catastrophic Yet Preventable

被引:0
作者
Nmadu, Yeka W. [1 ]
Bernhard, Joseph [2 ]
Klawinski, Amanda [3 ]
Klawinski, Darren [4 ]
Shah, Chetan [5 ]
Nakagawa, Thomas [6 ]
机构
[1] Univ Florida, Coll Med, Pediat, Jacksonville, FL 32610 USA
[2] Univ Florida, Coll Med, Emergency Med, Jacksonville, FL USA
[3] Univ S Florida, Obstet & Gynecol, Tampa, FL 33620 USA
[4] Nemours Childrens Hlth Syst, Pediat Hematol Oncol, Jacksonville, FL USA
[5] Nemours Childrens Hlth Syst, Pediat Radiol, Jacksonville, FL USA
[6] Univ Florida, Coll Med, Pediat Crit Care Med, Jacksonville, FL USA
关键词
seizures; hemorrhagic disease of the newborn; newborn; bleeding; vitamin k deficiency; REFUSAL; PROPHYLAXIS; INFANTS;
D O I
10.7759/cureus.64098
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A four-week-old full-term male infant presented to the emergency department with blood in the diaper, increasing lethargy, and vomiting and was found to have multiple intracranial hemorrhages on CT. He was delivered at home and did not receive vitamin K. Coagulation studies were abnormal, and des-gamma carboxyprothrombin (DCP) was 481, diagnostic of vitamin K deficiency. He received vitamin K and required multiple antiepileptic medications for seizure control. Vitamin K deficiency bleeding (VKDB) is a preventable disease that can have devastating consequences and could present as early, classical, or lateonset. The typical presentation manifests with cutaneous, gastrointestinal, or intracranial hemorrhage most commonly in fully breastfed infants. Vitamin K prophylaxis has proven to be effective. With increasing outof-hospital delivery and online misinformation, there is a declining administration of intramuscular vitamin K at birth. It is the responsibility of healthcare providers to properly inform patients and their families of the importance of vitamin K prophylaxis at or before the time of delivery.
引用
收藏
页数:5
相关论文
共 20 条
[1]  
[Anonymous], 2013, Pocket Book of Hospital Care for Children: Guidelines for the Management of Common Childhood Illnesses
[2]   Vitamin K Deficiency Bleeding in Infancy [J].
Araki, Shunsuke ;
Shirahata, Akira .
NUTRIENTS, 2020, 12 (03)
[3]   Vitamin K deficiency bleeding in an apparently healthy newborn infant: the compelling need for evidence-based recommendation [J].
Ceratto, Simone ;
Savino, Francesco .
ITALIAN JOURNAL OF PEDIATRICS, 2019, 45 (1)
[4]  
Danziger Phoebe, 2019, Hosp Pediatr, V9, P429, DOI 10.1542/hpeds.2019-0029
[5]  
Dekker R, 2019, Evid Based Birth
[6]  
Hamrick Harvey James, 2016, Hosp Pediatr, V6, P15, DOI 10.1542/hpeds.2015-0095
[7]   Vitamin K and the Newborn Infant [J].
Hand, Ivan ;
Noble, Lawrence ;
Abrams, Steven A. .
PEDIATRICS, 2022, 149 (03)
[8]   Investigation of Public Perception of Brain Death Using the Internet [J].
Jones, Amy H. ;
Dizon, Zoelle B. ;
October, Tessie W. .
CHEST, 2018, 154 (02) :286-292
[9]   Vitamin K prophylaxis in newborns [J].
Jullien, Sophie .
BMC PEDIATRICS, 2021, 21 (SUPPL 1)
[10]  
Loyal Jaspreet, 2020, Hosp Pediatr, V10, P286, DOI 10.1542/hpeds.2019-0228