Eosinophilic Esophagitis: The Role of Steroids and the Dose, Duration, and Delivery of Steroid Therapy

被引：1
作者：
Ramanan, Sruthi Priyavadhana [1 ,2 ,3 ]
Singh, Bipneet [3 ]
Gandhamaneni, Sri Harshini [4 ]
Sange, Ibrahim [1 ,5 ]
机构：
[1] Calif Inst Behav Neurosci & Psychol, Res, Fairfield, CA 94534 USA
[2] Saveetha Med Coll, Med Surg, Chennai, India
[3] Henry Ford Hlth Syst, Internal Med, Jackson, MI 49201 USA
[4] Saveetha Med Coll, Internal Med, Chennai, India
[5] Karamshibhai Jethabhai Somaiya Med Coll Hosp & Re, Internal Med, Mumbai, India
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 04期
关键词：
eosinophilic esophagitis; steroids; budesonide; ciclesonide; fluticasone; PLACEBO-CONTROLLED TRIAL; FLUTICASONE PROPIONATE; CHILDREN; DIAGNOSIS; MANAGEMENT; RECOMMENDATIONS; CICLESONIDE; HEALTH;
D O I：
10.7759/cureus.58343
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Eosinophilic esophagitis (EoE) is a chronic immune -mediated condition characterized by the eosinophil infiltration of the esophagus (>15 per high power field). Recently, there has been an increase in both the incidence and prevalence of the disease. The common modalities of treatment are dietary modification, proton pump inhibitors, and steroids. However, the United States Food and Drug Administration has not approved any drugs for the treatment of EoE. This review has discussed the role of steroids in the treatment of EoE, focusing on the various formulations of the drug, its dosage, drug delivery, and duration of therapy. The study also covers the common outcomes of steroid therapy and its side effects.
引用
收藏
页数：8
相关论文
共 37 条
  • [1] Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis
    Alexander, Eileen S.
    Martin, Lisa J.
    Collins, Margaret H.
    Kottyan, Leah C.
    Sucharew, Heidi
    He, Hua
    Mukkada, Vincent A.
    Succop, Paul A.
    Abonia, J. Pablo
    Foote, Heather
    Eby, Michael D.
    Grotjan, Tommie M.
    Greenler, Alexandria J.
    Dellon, Evan S.
    Demain, Jeffrey G.
    Furuta, Glenn T.
    Gurian, Larry E.
    Harley, John B.
    Hopp, Russell J.
    Kagalwalla, Amir
    Kaul, Ajay
    Nadeau, Kari C.
    Noel, Richard J.
    Putnam, Philip E.
    von Tiehl, Karl F.
    Rothenberg, Marc E.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (05) : 1084 - +
  • [2] Swallowed Fluticasone Propionate Is an Effective Long-Term Maintenance Therapy for Children With Eosinophilic Esophagitis
    Andreae, Doerthe A.
    Hanna, Matthew G.
    Magid, Margret S.
    Malerba, Stefano
    Andreae, Michael H.
    Bagiella, Emilia
    Chehade, Mirna
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 (08) : 1187 - 1197
  • [3] Efficacy, Dose Reduction, and Resistance to High-Dose Fluticasone in Patients With Eosinophilic Esophagitis
    Butz, Bridget K.
    Wen, Ting
    Gleich, Gerald J.
    Furuta, Glenn T.
    Spergel, Jonathan
    King, Eileen
    Kramer, Robert E.
    Collins, Margaret H.
    Stucke, Emily
    Mangeot, Colleen
    Jackson, W. Daniel
    O'Gorman, Molly
    Abonia, J. Pablo
    Pentiuk, Scott
    Putnam, Philip E.
    Rothenberg, Marc E.
    [J]. GASTROENTEROLOGY, 2014, 147 (02) : 324 - +
  • [4] Efficacy of Budesonide vs Fluticasone for Initial Treatment of Eosinophilic Esophagitis in a Randomized Controlled Trial
    Dellon, Evan S.
    Woosley, John T.
    Arrington, Ashley
    McGee, Sarah J.
    Covington, Jacquelyn
    Moist, Susan E.
    Gebhart, Jessica H.
    Tylicki, Alexandra E.
    Shoyoye, Shiyan O.
    Martin, Christopher F.
    Galanko, Joseph A.
    Baron, John A.
    Shaheen, Nicholas J.
    [J]. GASTROENTEROLOGY, 2019, 157 (01) : 65 - +
  • [5] Safety and Efficacy of Budesonide Oral Suspension Maintenance Therapy in Patients With Eosinophilic Esophagitis
    Dellon, Evan S.
    Katzka, David A.
    Collins, Margaret H.
    Gupta, Sandeep K.
    Lan, Lan
    Williams, James
    Hirano, Ikuo
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2019, 17 (04) : 666 - +
  • [6] Epidemiology and Natural History of Eosinophilic Esophagitis
    Dellon, Evan S.
    Hirano, Ikuo
    [J]. GASTROENTEROLOGY, 2018, 154 (02) : 319 - +
  • [7] Budesonide Oral Suspension Improves Symptomatic, Endoscopic, and Histologic Parameters Compared With Placebo in Patients With Eosinophilic Esophagitis
    Dellon, Evan S.
    Katzka, David A.
    Collins, Margaret H.
    Hamdani, Mohamed
    Gupta, Sandeep K.
    Hirano, Ikuo
    [J]. GASTROENTEROLOGY, 2017, 152 (04) : 776 - +
  • [8] ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE)
    Dellon, Evan S.
    Gonsalves, Nirmala
    Hirano, Ikuo
    Furuta, Glenn T.
    Liacouras, Chris A.
    Katzka, David A.
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2013, 108 (05) : 679 - 692
  • [9] Viscous Topical Is More Effective Than Nebulized Steroid Therapy for Patients With Eosinophilic Esophagitis
    Dellon, Evan S.
    Sheikh, Arif
    Speck, Olga
    Woodward, Kimberly
    Whitlow, Ann B.
    Hores, Jessica M.
    Ivanovic, Marija
    Chau, Allen
    Woosley, John T.
    Madanick, Ryan D.
    Orlando, Roy C.
    Shaheen, Nicholas J.
    [J]. GASTROENTEROLOGY, 2012, 143 (02) : 321 - +
  • [10] Treatment of eosinophilic esophagitis with inhaled corticosteroids
    Faubion, WA
    Perrault, J
    Burgart, LJ
    Zein, NN
    Clawson, M
    Freese, DK
    [J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1998, 27 (01) : 90 - 93
1234