Coastal natural products: a review applied to antimycobacterial activity

被引：0

作者：

Baptista, Rodolfo Moreira ^{[1
]}

Rodrigues, Marcos Alaniz ^{[1
]}

Roselet, Fabio ^{[2
]}

Costa, Cesar Serra Bonifacio ^{[2
]}

da Silva, Pedro Eduardo Almeida ^{[1
]}

Ramos, Daniela Fernandes ^{[1
]}

机构：

[1] Univ Fed Rio Grande, Lab Bioprospeccao Prod Nat Costeiros, Rio Grande, Brazil

[2] Univ Fed Rio Grande, Inst Oceanol, Rio Grande, Brazil

来源：

NATURAL PRODUCT RESEARCH | 2025年 / 39卷 / 06期

关键词：

Coastal environments; natural products; Mycobacterium tuberculosis; antimicrobial; MANGROVE ENDOPHYTIC FUNGUS; PATOS LAGOON ESTUARY; MYCOBACTERIUM-TUBERCULOSIS; DERIVATIVES; INHIBITORS; BIODIVERSITY; MECHANISM; ACID;

D O I：

10.1080/14786419.2024.2361333

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Despite the many advances in drug research, natural products are still being explored as a promising source for discovering new bioactive compounds to treat global diseases such as tuberculosis. However, there is a lack of studies and information about coastal natural products, which thrive in the transitional environment between two different ecosystems and produce unique secondary metabolites. Mangroves, estuaries, and mudflats make up areas for coastal species and have shown promising results in antituberculosis research, some of them are present in hotspot areas. This review focuses on research conducted in coastal environments and explores the reasons why these natural products tend to outperform non-coastal ones against the causative agent of tuberculosis, Mycobacterium tuberculosis.

引用

页码：1607 / 1621

页数：15

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