Case report: management of a young male patient with diabetic ketoacidosis and thyroid storm

被引:0
作者
Huang, Xiaoyu [1 ]
Chen, Yan [2 ]
Huang, Xinwei [2 ]
Tang, Jiahao [2 ]
机构
[1] Sun Yat Sen Univ, Affiliated Hosp 7, Emergency & Disaster Med Ctr, Shenzhen, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 7, Dept Endocrinol, Shenzhen, Peoples R China
来源
FRONTIERS IN ENDOCRINOLOGY | 2024年 / 15卷
关键词
diabetic ketoacidosis; thyroid storm; recurrent diabetic ketoacidosis; autoimmune polyendocrine syndrome; case report; ASSOCIATION; MELLITUS; HLA; THYROTOXICOSIS; DYSFUNCTION; HYPOTHERMIA; PREVALENCE; HORMONE; DISEASE;
D O I
10.3389/fendo.2024.1403893
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This report describes a case of concomitant diabetic ketoacidosis (DKA) and thyroid storm (TS) in a 20-year-old male patient that presented both diagnostic and management challenges owing to their intricate interrelationship in endocrine-metabolic disorders. The patient, previously diagnosed with type 1 diabetes mellitus (T1DM) and hyperthyroidism, was admitted to the emergency department with symptoms of DKA and progressive exacerbation of TS. Initial treatment focused on correcting DKA; as the disease progressed to TS, it was promptly recognized and treated. This case emphasizes the rarity of simultaneous occurrence of DKA and TS, as well as the challenges in clinical diagnosis posed by the interacting pathophysiological processes and overlapping clinical manifestations of DKA and TS. The patient's treatment process involved multiple disciplines, and after treatment, the patient's critical condition of both endocrine metabolic diseases was alleviated, after which he recovered and was eventually discharged from the hospital. This case report aims to emphasize the need for heightened awareness in patients with complex clinical presentations, stress the possibility of concurrent complications, and underscore the importance of prompt and collaborative treatment strategies.
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页数:7
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共 34 条
  • [11] Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease
    Eriksson, D.
    Bianchi, M.
    Landegren, N.
    Nordin, J.
    Dalin, F.
    Mathioudaki, A.
    Eriksson, G. N.
    Hultin-Rosenberg, L.
    Dahlqvist, J.
    Zetterqvist, H.
    Karlsson, A.
    Hallgren, A.
    Farias, F. H. G.
    Muren, E.
    Ahlgren, K. M.
    Lobell, A.
    Andersson, G.
    Tandre, K.
    Dahlqvist, S. R.
    Soderkvist, P.
    Ronnblom, L.
    Hulting, A. -L.
    Wahlberg, J.
    Ekwall, O.
    Dahlqvist, P.
    Meadows, J. R. S.
    Bensing, S.
    Lindblad-Toh, K.
    Kampe, O.
    Pielberg, G. R.
    [J]. JOURNAL OF INTERNAL MEDICINE, 2016, 280 (06) : 595 - 608
  • [12] Incidence and prevalence of diabetic ketoacidosis (DKA) among adults with type 1 diabetes mellitus (T1D): a systematic literature review
    Farsani, Soulmaz Fazeli
    Brodovicz, Kimberly
    Soleymanlou, Nima
    Marquard, Jan
    Wissinger, Erika
    Maiese, Brett A.
    [J]. BMJ OPEN, 2017, 7 (07):
  • [13] Glucose tolerance, insulin secretion, insulin sensitivity and glucose effectiveness in normal and overweight hyperthyroid women
    Gonzalo, A
    Grant, C
    Moreno, I
    Garcia, FJ
    Suarez, AI
    HerreraPombo, JL
    Rovira, A
    [J]. CLINICAL ENDOCRINOLOGY, 1996, 45 (06) : 689 - 697
  • [14] Follow-Up Analysis of Genome-Wide Association Data Identifies Novel Loci for Type 1 Diabetes
    Grant, Struan F. A.
    Qu, Hui-Qi
    Bradfield, Jonathan P.
    Marchand, Luc
    Kim, Cecilia E.
    Glessner, Joseph T.
    Grabs, Rosemarie
    Taback, Shayne P.
    Frackelton, Edward C.
    Eckert, Andrew W.
    Annaiah, Kiran
    Lawson, Margaret L.
    Otieno, F. George
    Santa, Erin
    Shaner, Julie L.
    Smith, Ryan M.
    Skraban, Robert
    Imielinski, Marcin
    Chiavacci, Rosetta M.
    Grundmeier, Robert W.
    Stanley, Charles A.
    Kirsch, Susan E.
    Waggott, Daryl
    Paterson, Andrew D.
    Monos, Dimitri S.
    Polychronakos, Constantin
    Hakonarson, Hakon
    [J]. DIABETES, 2009, 58 (01) : 290 - 295
  • [15] Gursoy N., 1999, The relationship between the glycemic control and the hypothalamus-pituitary-thyroid axis in diabetic patients
  • [16] THYROID-HORMONE AND THE GUT
    HAYS, MT
    [J]. ENDOCRINE RESEARCH, 1988, 14 (2-3) : 203 - 224
  • [17] Khassawneh AH, 2020, INT J GEN MED, V13, P803, DOI [10.2147/IJGM.S273900, 10.2147/IJGM.S279300]
  • [18] Hyperglycemic Crises in Adult Patients with Diabetes
    Kitabchi, Abbas E.
    Umpierrez, Guillermo E.
    Miles, John M.
    Fisher, Joseph N.
    [J]. DIABETES CARE, 2009, 32 (07) : 1335 - 1343
  • [19] Thyrotoxicosis masked by diabetic ketoacidosis - A fatal complication
    Kunishige, M
    Sekimoto, E
    Komatsu, M
    Bando, Y
    Uehara, H
    Izumi, K
    [J]. DIABETES CARE, 2001, 24 (01) : 171 - 171
  • [20] Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    Lowe, Christopher E.
    Cooper, Jason D.
    Brusko, Todd
    Walker, Neil M.
    Smyth, Deborah J.
    Bailey, Rebecca
    Bourget, Kirsi
    Plagnol, Vincent
    Field, Sarah
    Atkinson, Mark
    Clayton, David G.
    Wicker, Linda S.
    Todd, John A.
    [J]. NATURE GENETICS, 2007, 39 (09) : 1074 - 1082