Efficacy of User Self-Led and Human-Supported Digital Health Interventions for People With Schizophrenia: A Systematic Review and Meta-Analysis

被引:1
作者
Arnautovska, Urska [1 ,2 ,3 ]
Trott, Mike [1 ,2 ,3 ]
Vitangcol, Kathryn Jemimah [1 ]
Milton, Alyssa [4 ]
Brown, Ellie [5 ]
Warren, Nicola [1 ,2 ,3 ]
Leucht, Stefan [6 ]
Firth, Joseph [7 ]
Siskind, Dan [1 ,2 ,3 ]
机构
[1] Univ Queensland, Fac Med, Med Sch, Brisbane, Qld, Australia
[2] Metro South Hlth, Addict & Mental Hlth Serv, Brisbane, Qld, Australia
[3] Queensland Ctr Mental Hlth Res, Wacol, Qld, Australia
[4] Univ Sydney, Fac Med & Hlth, Cent Clin Sch, Sydney, NSW, Australia
[5] Natl Ctr Excellence Youth Mental Hlth, Orygen, Parkville, Vic, Australia
[6] Tech Univ Munich, TUM Sch Med & Hlth, Dept Psychiat & Psychotherapy, Munich, Germany
[7] Univ Manchester, Manchester Acad Hlth Sci Ctr, Div Psychol & Mental Hlth, Manchester, England
基金
英国科研创新办公室; 澳大利亚国家健康与医学研究理事会; 澳大利亚研究理事会;
关键词
eHealth; psychosis; self-management; mobile apps; computer; ANTIPSYCHOTIC MEDICATION; ENHANCING ADHERENCE; PSYCHOSIS; ONLINE; INDIVIDUALS; PERSPECTIVE; MANAGEMENT; SYMPTOMS; STRATEGY; QUALITY;
D O I
10.1093/schbul/sbae143
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background Digital health interventions (DHIs) may enable low cost, scalable improvements in the quality of care for adults with schizophrenia. Given the fast-growing number of studies using these tools, this review aimed to assess the efficacy and feasibility of randomized controlled trials (RCTs) of DHIs among people with schizophrenia, focusing on human support.Design A systematic search of PubMed, Embase, PsycINFO, CINAHL, Web of Science, and Cochrane databases was conducted in January 2024 to identify relevant RCTs. Random effects meta-analyses were undertaken to evaluate the effects on psychosis symptoms, cognition, and other health-related outcomes.Results Twenty-six RCTs (n = 2481 participants) were included. Pooled recruitment and retention rates were 57.4% and 87.6%, respectively. DHIs showed no statistically significant effect sizes across all examined outcomes, including psychosis symptoms, depression, quality of life, global and social cognition, global and social functioning, and medication adherence. A third (34.6%) of DHIs were developed using co-design while the majority (70%) personalized the intervention to its users and 69.2% were deemed to be at high risk of bias. There were trends toward effects in favor of DHIs with human support for social cognition and quality of life.Conclusions DHIs are feasible for people with schizophrenia and potentially useful for improving health outcomes, particularly when including human support. More high-quality studies are required to examine the benefits of human support within DHIs. Future research should examine the feasibility of sustained adherence and benefits from digital interventions, possibly incorporating human interaction complemented with artificial intelligence, in real-world clinical settings.
引用
收藏
页数:15
相关论文
共 87 条
  • [1] THE THEORY OF PLANNED BEHAVIOR
    AJZEN, I
    [J]. ORGANIZATIONAL BEHAVIOR AND HUMAN DECISION PROCESSES, 1991, 50 (02) : 179 - 211
  • [2] Online, social media and mobile technologies for psychosis treatment: A systematic review on novel user-led interventions
    Alvarez-Jimenez, M.
    Alcazar-Corcoles, M. A.
    Gonzalez-Blanch, C.
    Bendall, S.
    McGorry, P. D.
    Gleeson, J. F.
    [J]. SCHIZOPHRENIA RESEARCH, 2014, 156 (01) : 96 - 106
  • [3] The Horyzons project: a randomized controlled trial of a novel online social therapy to maintain treatment effects from specialist first-episode psychosis services
    Alvarez-Jimenez, Mario
    Koval, Peter
    Schmaal, Lianne
    Bendall, Sarah
    O'Sullivan, Shaunagh
    Cagliarini, Daniela
    D'Alfonso, Simon
    Rice, Simon
    Valentine, Lee
    Penn, David L.
    Miles, Chris
    Russon, Penni
    Phillips, Jessica
    McEnery, Carla
    Lederman, Reeva
    Killackey, Eoin
    Mihalopoulos, Cathrine
    Gonzalez-Blanch, Cesar
    Gilbertson, Tamsyn
    Lal, Shalini
    Cotton, Sue Maree
    Herrman, Helen
    McGorry, Patrick D.
    Gleeson, John F. M.
    [J]. WORLD PSYCHIATRY, 2021, 20 (02) : 233 - 243
  • [4] Factors affecting implementation of digital health interventions for people with psychosis or bipolar disorder, and their family and friends: a systematic review
    Aref-Adib, Golnar
    McCloud, Tayla
    Ross, Jamie
    O'Hanlon, Puffin
    Appleton, Victoria
    Rowe, Sarah
    Murray, Elizabeth
    Johnson, Sonia
    Lobban, Fiona
    [J]. LANCET PSYCHIATRY, 2019, 6 (03): : 257 - 266
  • [5] Arnautovska U., 2024, BJPysch Open
  • [6] The role of human involvement and support in digital mental health interventions for people with schizophrenia spectrum disorders: a critical review
    Arnautovska, Urska
    Milton, Alyssa
    Trott, Mike
    Soole, Rebecca
    Siskind, Dan
    [J]. CURRENT OPINION IN PSYCHIATRY, 2024, 37 (05) : 356 - 362
  • [7] Biopsychology of Physical Activity in People with Schizophrenia: An Integrative Perspective on Barriers and Intervention Strategies
    Arnautovska, Urska
    Kesby, James P.
    Korman, Nicole
    Rebar, Amanda L.
    Chapman, Justin
    Warren, Nicola
    Rossell, Susan L.
    Dark, Frances L.
    Siskind, Dan
    [J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2022, 18 : 2917 - 2926
  • [8] How to perform a meta-analysis with R: a practical tutorial
    Balduzzi, Sara
    Ruecker, Gerta
    Schwarzer, Guido
    [J]. EVIDENCE-BASED MENTAL HEALTH, 2019, 22 (04) : 153 - 160
  • [9] A Comparison of Telephone and Texting Interventions for Persons with Schizophrenia Spectrum Disorders
    Beebe, Lora
    Smith, Kathlene D.
    Phillips, Chad
    [J]. ISSUES IN MENTAL HEALTH NURSING, 2014, 35 (05) : 323 - 329
  • [10] Bell I.H., 2019, Current Treatment Options in Psychiatry, V6, P256, DOI [DOI 10.1007/S40501-019-00182-Y, 10.1007/s40501-019-00182-y]