Therapeutic potential of lipid-lowering probiotics on the atherosclerosis development

被引：1

作者：

Saadh, Mohamed J. ^{[1
]}

Bazghandi, Behina ^{[2
]}

Jamialahmdi, Hamid ^{[3
]}

Bajgiran, Fatemeh Rahimzadeh- ^{[4
]}

Forouzanfar, Fatemeh ^{[6
]}

Esmaeili, Seyed-Alireza ^{[5
]}

Saburi, Ehsan ^{[3
]}

机构：

[1] Middle East Univ, Fac Pharm, Amman 11831, Jordan

[2] Shahid Beheshti Univ, Prot Res Ctr, Tehran, Iran

[3] Mashhad Univ Med Sci, Med Genet Res Ctr, Mashhad, Iran

[4] Islamic Azad Univ, Dept Biol, Mashhad Branch, Mashhad, Iran

[5] Mashhad Univ Med Sci, Immunol Res Ctr, Mashhad, Iran

[6] Mashhad Univ Med Sci, Med Toxicol Res Ctr, Sch Med, Mashhad, Iran

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 2024年 / 971卷

关键词：

Atherosclerosis; Cholesterol; Hypercholesterolemia; Probiotic; TRIMETHYLAMINE-N-OXIDE; BILE-SALT HYDROLASE; LACTOBACILLUS-PLANTARUM STRAINS; CORONARY-ARTERY-DISEASE; INTESTINAL MICROBIOTA; GUT MICROBIOTA; L-CARNITINE; TOLEROGENIC PROBIOTICS; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME;

D O I：

10.1016/j.ejphar.2024.176527

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Hypercholesterolemia is a critical risk factor for atherosclerosis, mostly attributed to lifestyle behavior such as diet. Recent advances have emphasized the critical effects of gastrointestinal bacteria in the pathology of hypercholesterolemia and atherosclerosis, suggesting that the gastrointestinal microbiome can therefore provide efficient therapeutic targets for preventing and treating atherosclerosis. Thus, interventions, such as probiotic therapy, aimed at altering the bacterial composition introduce a promising therapeutic procedure. In the current review, we will provide an overview of anti-atherogenic probiotics contributing to lipid-lowering, inhibiting atherosclerotic inflammation, and suppressing bacterial atherogenic metabolites.

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页数：7

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共 83 条

[1] Natural regulatory T cells control the development of atherosclerosis in mice [J].

Ait-Oufella, H ;

Salomon, BL ;

Potteaux, S ;

Robertson, AKL ;

Gourdy, P ;

Zoll, J ;

Merval, R ;

Esposito, B ;

Cohen, JL ;

Fisson, S ;

Flavell, RA ;

Hansson, GK ;

Klatzmann, D ;

Tedgui, A ;

Mallat, Z .

NATURE MEDICINE, 2006, 12 (02) :178-180

[2] Adaptive (T and B Cells) Immunity and Control by Dendritic Cells in Atherosclerosis [J].

Ait-Oufella, Hafid ;

Sage, Andrew P. ;

Mallat, Ziad ;

Tedgui, Alain .

CIRCULATION RESEARCH, 2014, 114 (10) :1640-1660

[3] Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial [J].

Akkasheh, Ghodarz ;

Kashani-Poor, Zahra ;

Tajabadi-Ebrahimi, Maryam ;

Jafari, Parvaneh ;

Akbari, Hossein ;

Taghizadeh, Mohsen ;

Memarzadeh, Mohammad Reza ;

Asemi, Zatollah ;

Esmaillzadeh, Ahmad .

NUTRITION, 2016, 32 (03) :315-320

[4] Immunoregulatory Effects of Tolerogenic Probiotics in Multiple Sclerosis [J].

Atabati, Hadi ;

Yazdanpanah, Esmaeil ;

Mortazavi, Hamed ;

Bajestani, Saeed Gharibian ;

Raoofi, Amir ;

Esmaeili, Seyed-Alireza ;

Khaledi, Azad ;

Saburi, Ehsan ;

Afshari, Jalil Tavakol ;

Sathyapalan, Thozhukat ;

Moghaddam, Abbas Shapouri ;

Sahebkar, Amirhossein .

REVIEWS ON NEW DRUG TARGETS IN AGE-RELATED DISORDERS, PT II, 2021, 1286 :87-105

[5] Probiotics with ameliorating effects on the severity of skin inflammation in psoriasis: Evidence from experimental and clinical studies [J].

Atabati, Hadi ;

Esmaeili, Seyed-Alireza ;

Saburi, Ehsan ;

Akhlaghi, Maedeh ;

Raoofi, Amir ;

Rezaei, Nima ;

Momtazi-Borojeni, Amir Abbas .

JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 235 (12) :8925-8937

[6] Probiotic Supplementation and Trimethylamine-N-Oxide Production Following a High-Fat Diet [J].

Boutagy, Nabil E. ;

Neilson, Andrew P. ;

Osterberg, Kristin L. ;

Smithson, Andrew T. ;

Englund, Tessa R. ;

Davy, Brenda M. ;

Hulver, Matthew W. ;

Davy, Kevin P. .

OBESITY, 2015, 23 (12) :2357-2363

[7] Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice [J].

Braun, Anne ;

Yesilaltay, Ayce ;

Acton, Susan ;

Broschat, Kay O. ;

Krul, Elaine S. ;

Napawan, Nida ;

Stagliano, Nancy ;

Krieger, Monty .

ATHEROSCLEROSIS, 2008, 198 (01) :77-84

[8] Impairment of the Programmed Cell Death-1 Pathway Increases Atherosclerotic Lesion Development and Inflammation [J].

Bu, De-xiu ;

Tarrio, Margarite ;

Maganto-Garcia, Elena ;

Stavrakis, George ;

Tajima, Goro ;

Lederer, James ;

Jarolim, Petr ;

Freeman, Gordon J. ;

Sharpe, Arlene H. ;

Lichtman, Andrew H. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2011, 31 (05) :1100-U411

[9] B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice [J].

Buono, C ;

Pang, H ;

Uchida, Y ;

Libby, P ;

Sharpe, AH ;

Lichtman, AH .

CIRCULATION, 2004, 109 (16) :2009-2015

[10] Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding [J].

Cani, P. D. ;

Delzenne, N. M. ;

Amar, J. ;

Burcelin, R. .

PATHOLOGIE BIOLOGIE, 2008, 56 (05) :305-309

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