Inflammatory Markers in Thyroid Eye Disease: A Meta-Analysis

被引:1
作者
Chuang, Shu-Han [1 ]
Chang, Cheng-Hsien [2 ,3 ]
机构
[1] Changhua Christian Hosp, Dept Med Educ, Div Gen Practice, Changhua, Taiwan
[2] Changhua Christian Hosp, Dept Ophthalmol, 135 Nanxiao St, Changhua 500209, Taiwan
[3] Natl Chung Hsing Univ, Coll Med, Dept Postbaccalaureate Med, Taichung, Taiwan
关键词
Meta-analysis; monocyte-to-lymphocyte ratio; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; thyroid eye disease; TO-LYMPHOCYTE RATIO; GRAVES ORBITOPATHY; EUROPEAN GROUP; NEUTROPHIL; MANAGEMENT;
D O I
10.1080/07435800.2024.2362787
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thyroid Eye Disease (TED) is an inflammatory autoimmune condition affecting the eyes, often associated with Graves' disease. Inflammation is important in TED, involving immune cells and orbital tissues. While inflammatory markers have been studied in other diseases, their role in TED is unclear. We included 734 participants from 5 eligible studies investigated associations between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) and TED. Initial analysis found no significant differences in these markers between TED and control groups. However, sensitivity analysis excluding an outlier study revealed significant differences in NLR, PLR, and MLR between groups, suggesting the potential association between these inflammatory markers and TED. More research is needed, but these findings indicate complex TED pathogenesis and that inflammation may offer insights for TED diagnosis and management.
引用
收藏
页码:193 / 202
页数:10
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