A Review of the Evolving Role of Radiotherapy in the Treatment of Neuroendocrine Neoplasms

被引:1
作者
Yit, Ling Fung Nelson [1 ,2 ]
Li, Youquan [1 ,2 ]
机构
[1] Natl Canc Ctr Singapore, Div Radiat Oncol, Singapore, Singapore
[2] Duke NUS Med Sch, Singapore, Singapore
关键词
Image-guided radiation therapy; Intensity-modulated radiotherapy; Stereotactic body radiotherapy; Radiotherapy; Neuroendocrine neoplasms; Neuroendocrine carcinoma; CLINICAL-PRACTICE GUIDELINES; ENETS CONSENSUS GUIDELINES; MERKEL CELL-CARCINOMA; EXTERNAL-BEAM RADIATION; PROGNOSTIC-FACTORS; SYSTEMIC THERAPY; MANAGEMENT; DIAGNOSIS; CANCER; TUMORS;
D O I
10.1159/000538140
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Neuroendocrine neoplasms (NENs) are rare tumours that develop from neuroendocrine cells in various parts of the body. The management of this disease poses a significant challenge because of the heterogeneous clinical presentation and varying degrees of aggressiveness. A multidisciplinary approach is often required in complex clinical situations. Radiotherapy (RT) plays a key role in managing NETs in both curative and palliative settings. Summary: In this review, we summarize and discuss recent developments in the field of advanced RT in early-stage, locally advanced, and metastatic NENs. We highlight limitations in current approaches and discuss future potential treatment strategies for patients with NENs.
引用
收藏
页码:856 / 865
页数:10
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