A Review of the Evolving Role of Radiotherapy in the Treatment of Neuroendocrine Neoplasms

被引:1
作者
Yit, Ling Fung Nelson [1 ,2 ]
Li, Youquan [1 ,2 ]
机构
[1] Natl Canc Ctr Singapore, Div Radiat Oncol, Singapore, Singapore
[2] Duke NUS Med Sch, Singapore, Singapore
关键词
Image-guided radiation therapy; Intensity-modulated radiotherapy; Stereotactic body radiotherapy; Radiotherapy; Neuroendocrine neoplasms; Neuroendocrine carcinoma; CLINICAL-PRACTICE GUIDELINES; ENETS CONSENSUS GUIDELINES; MERKEL CELL-CARCINOMA; EXTERNAL-BEAM RADIATION; PROGNOSTIC-FACTORS; SYSTEMIC THERAPY; MANAGEMENT; DIAGNOSIS; CANCER; TUMORS;
D O I
10.1159/000538140
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Neuroendocrine neoplasms (NENs) are rare tumours that develop from neuroendocrine cells in various parts of the body. The management of this disease poses a significant challenge because of the heterogeneous clinical presentation and varying degrees of aggressiveness. A multidisciplinary approach is often required in complex clinical situations. Radiotherapy (RT) plays a key role in managing NETs in both curative and palliative settings. Summary: In this review, we summarize and discuss recent developments in the field of advanced RT in early-stage, locally advanced, and metastatic NENs. We highlight limitations in current approaches and discuss future potential treatment strategies for patients with NENs.
引用
收藏
页码:856 / 865
页数:10
相关论文
共 103 条
[1]   Combining External Beam Radiation and Radionuclide Therapies: Rationale, Radiobiology, Results and Roadblocks [J].
Abbott, E. M. ;
Falzone, N. ;
Lenzo, N. ;
Vallis, K. A. .
CLINICAL ONCOLOGY, 2021, 33 (11) :735-743
[2]   Current and emerging therapies for neuroendocrine prostate cancer [J].
Alabi, Busola Ruth ;
Liu, Shiqin ;
Stoyanova, Tanya .
PHARMACOLOGY & THERAPEUTICS, 2022, 238
[3]   High-Grade Gastrointestinal Neuroendocrine Carcinoma Management and Outcomes: A National Cancer Database Study [J].
Alese, Olatunji B. ;
Jiang, Renjian ;
Shaib, Walid ;
Wu, Christina ;
Akce, Mehmet ;
Behera, Madhusmita ;
El-Raycs, Bassel F. .
ONCOLOGIST, 2019, 24 (07) :911-920
[4]   Multimodality Management of "Borderline Resectable" Pancreatic Neuroendocrine Tumors: Report of a Single-Institution Experience [J].
Ambe, Chenwi M. ;
Phuong Nguyen ;
Centeno, Barbara A. ;
Choi, Junsung ;
Strosberg, Jonathan ;
Kvols, Larry ;
Hodul, Pamela ;
Hoffe, Sarah ;
Malafa, Mokenge P. .
CANCER CONTROL, 2017, 24 (05)
[5]   Management of nonsinonasal neuroendocrine carcinomas of the head and neck [J].
Barker, JL ;
Glisson, BS ;
Garden, AS ;
El-Naggar, AK ;
Morrison, WH ;
Ang, KK ;
Chao, KSC ;
Clayman, G ;
Rosenthal, DI .
CANCER, 2003, 98 (11) :2322-2328
[6]   Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up [J].
Baudin, E. ;
Caplin, M. ;
Garcia-Carbonero, R. ;
Fazio, N. ;
Ferolla, P. ;
Filosso, P. L. ;
Frilling, A. ;
de Herder, W. W. ;
Hoersch, D. ;
Knigge, U. ;
Korse, C. M. ;
Lim, E. ;
Lombard-Bohas, C. ;
Pavel, M. ;
Scoazec, J. Y. ;
Sundin, A. ;
Berruti, A. .
ANNALS OF ONCOLOGY, 2021, 32 (04) :439-451
[7]   Merkel Cell Carcinoma, Version 1.2018 Clinical Practice Guidelines in Oncology [J].
Bichakjian, Christopher K. ;
Olencki, Thomas ;
Aasi, Sumaira Z. ;
Alam, Murad ;
Andersen, James S. ;
Blitzblau, Rachel ;
Bowen, Glen M. ;
Contreras, Carlo M. ;
Daniels, Gregory A. ;
Decker, Roy ;
Farma, Jeffrey M. ;
Fisher, Kris ;
Gastman, Brian ;
Ghosh, Karthik ;
Grekin, Roy C. ;
Grossman, Kenneth ;
Ho, Alan L. ;
Lewis, Karl D. ;
Loss, Manisha ;
Lydiatt, Daniel D. ;
Messina, Jane ;
Nehal, Kishwer S. ;
Nghiem, Paul ;
Puzanov, Igor ;
Schmults, Chrysalyne D. ;
Shaha, Ashok R. ;
Thomas, Valencia ;
Xu, Yaohui G. ;
Zic, John A. ;
Hoffmann, Karin G. ;
Engh, Anita M. .
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2018, 16 (06) :742-774
[8]   External beam radiation therapy for advanced/unresectable malignant paraganglioma and pheochromocytoma [J].
Breen, William ;
Bancos, Irina ;
Young, William F., Jr. ;
Bible, Keith C. ;
Laack, Nadia N. ;
Foote, Robert L. ;
Hallemeier, Christopher L. .
ADVANCES IN RADIATION ONCOLOGY, 2018, 3 (01) :25-29
[9]   A Review of Theranostics: Perspectives on Emerging Approaches and Clinical Advancements [J].
Burkett, Brian J. ;
Bartlett, David J. ;
Mcgarrah, Patrick W. ;
Lewis, Akeem R. ;
Johnson, Derek R. ;
Berberoglu, Kezban ;
Pandey, Mukesh K. ;
Packard, Annie T. ;
Halfdanarson, Thorvardur R. ;
Hruska, Carrie B. ;
Johnson, Geoffrey B. ;
Kendi, Tuba .
RADIOLOGY-IMAGING CANCER, 2023, 5 (04)
[10]   A role for radiotherapy in the management of advanced medullary thyroid carcinoma: the Mayo Clinic experience [J].
Call, Jason A. ;
Caudill, Jonathan S. ;
McIver, Bryan ;
Foote, Robert L. .
RARE TUMORS, 2013, 5 (03) :128-131