Photoredox/copper-catalyzed gem-difluoroalkylation-cyanation of 1,3-enynes

被引：1
|
作者：
Wang, Yachen [1 ]
Liu, Shuai [2 ]
Huang, Yangen [1 ]
机构：
[1] Donghua Univ, Coll Chem & Chem Engn, 2999 North Renmin Lu, Shanghai 201620, Peoples R China
[2] Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 24期
基金：
中国国家自然科学基金;
关键词：
LIGHT-INDUCED HYDRODIFLUOROMETHYLATION; RADICAL DIFLUOROMETHYLATION; ALKENES; ACCESS; THIOLS;
D O I：
10.1039/d4ob00602j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A photoredox/copper-catalyzed 1,4-difunctionalization of 1,3-enynes with readily available difluoroalkylating reagents and TMSCN was developed. This reaction proceeded at mild conditions, affording the corresponding difluoroalkylated allenes in good yields with high functional-group tolerance and excellent regioselectivity.
引用
收藏
页码：4895 / 4900
页数：6
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