Treatment and management of medullary thyroid microcarcinoma: a 10-year retrospective study from a single center

被引：1
作者：
Liu, Bin [1 ,2 ]
Peng, Ying [1 ]
Su, Yanjun [1 ]
Diao, Chang [1 ]
Cheng, Ruochuan [1 ]
机构：
[1] Kunming Med Univ, Affiliated Hosp 1, Thyroid Dis Diag & Treatment Ctr, Kunming, Yunnan, Peoples R China
[2] Kunming Med Univ, Kunming, Yunnan, Peoples R China
来源：
ENDOCRINE | 2024年 / 86卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Medullary thyroid microcarcinoma; Guidelines; Surgical treatment; Management; CLINICAL-PRACTICE GUIDELINES; CANCER INCIDENCE; CARCINOMA; TRENDS; DIAGNOSIS; PROGNOSIS; SURVIVAL;
D O I：
10.1007/s12020-024-03958-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
ObjectiveTo explore individualized treatment and management methods for medullary thyroid microcarcinoma (MTMC).MethodsClinical data of patients with medullary thyroid carcinoma with a diameter <= 1 cm admitted to the First Affiliated Hospital of Kunming Medical University from June 2013 to June 20x were collected. Combined with different treatment guidelines for medullary thyroid carcinoma, factors affecting lymph node metastasis and postoperative disease status were analyzed.ResultsTwenty-nine patients with MTMC were included in the analysis, including 24 patients who underwent total thyroidectomy, 5 who underwent thyroid gland lobectomy, and 13 who experienced postoperative lymph node metastasis. Multifocal tumor and calcitonin (Ctn) were the influencing factors, while multifocal tumor, Ctn, lymph node metastasis, and AJCC stage affected the dynamic risk stratification of postoperative disease.ConclusionCalcitonin detection is an important method for detecting MTMC. A tumor diameter <= 1 cm does not indicate that the tumor is in the early stage. The presence of multifocal tumors and Ctn should be used as important indicators for preoperative evaluation. Dynamic stratified risk assessment is critical in postoperative follow-up.
引用
收藏
页码：1081 / 1089
页数：9
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