Advances in self-assembled nanotechnology in tumor therapy

被引:0
作者
Kuang, Yanting [1 ]
Li, Zhaokai [1 ]
Chen, Hang [2 ]
Wang, Xinyu [2 ]
Wen, Yan [3 ]
Chen, Jianming [1 ,2 ]
机构
[1] Inner Mongolia Med Univ, 5 Xinhua Rd, Hohhot 010059, Inner Mongolia, Peoples R China
[2] Shanghai Wei Er Lab, Shanghai 201707, Peoples R China
[3] Naval Med Univ, Changzheng Hosp, Dept Pharm, 415 Fengyang Rd, Shanghai 200003, Peoples R China
关键词
Self; -assembly; Nanotechnology; Delivery system; Tumor therapy; CARRIER-FREE NANODRUGS; DRUG-DELIVERY; IN-VITRO; POLYMERIC MICELLES; CANCER-THERAPY; NANOPARTICLES; PRODRUG; EFFICACY; VIVO; MICROENVIRONMENT;
D O I
10.1016/j.colsurfb.2024.113838
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The emergence of nanotechnology has opened up a new way for tumor therapy. Among them, self-assembled nanotechnology has received extensive attention in medicine due to its simple preparation process, high drugloading capacity, low toxicity, and low cost. This review mainly summarizes the preparation methods of selfassembled nano-delivery systems, as well as the self-assembled mechanism of carrier-free nanomedicine, polymer-carried nanomedicine, polypeptide, and metal drugs, and their applications in tumor therapy. In addition, we discuss the advantages and disadvantages, future challenges, and opportunities of these selfassembled nanomedicines, which provide important references for the development and application of selfassembled nanotechnology in the field of medical therapy.
引用
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页数:9
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