Association of lifestyle and occupational exposure factors with human semen quality: a cross-sectional study of 1060 participants

被引：2

作者：

Yang, Wen ^{[1
,2
,3
]}

Duan, Zongliu ^{[1
,2
,3
]}

Li, Guanjian ^{[1
,2
,3
]}

Geng, Hao ^{[1
,2
,3
]}

Gao, Yang ^{[1
,2
,3
]}

Shen, Qunshan ^{[1
,2
,3
]}

Liu, Liting ^{[1
,2
,3
]}

Wang, Guanxiong ^{[1
,2
,3
]}

Zha, Xiaomin ^{[1
,2
,3
]}

Xu, Chuan ^{[1
,2
,3
]}

Zhou, Ping ^{[1
,2
,3
]}

Song, Bing ^{[1
,2
,3
]}

Tang, Dongdong ^{[1
,2
,3
]}

Wu, Huan ^{[1
,2
,3
]}

Wei, Zhaolian ^{[1
,2
,3
]}

Tang, Feng ^{[5
]}

He, Xiaojin ^{[1
,2
,4
]}

机构：

[1] Anhui Med Univ, Affiliated Hosp 1, Reprod Med Ctr, Dept Obstet & Gynecol, Hefei 230022, Anhui, Peoples R China

[2] Anhui Med Univ, NHC Key Lab Study Abnormal Gametes & Reprod Tract, Hefei, Anhui, Peoples R China

[3] Anhui Med Univ, Key Lab Populat Hlth Life Cycle, Minist Educ Peoples Republ China, Hefei, Anhui, Peoples R China

[4] Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Reprod Med Ctr, Sch Med, Shanghai, Peoples R China

[5] Zhejiang Mater Child & Reprod Hlth Ctr, 256,WanTang Rd, Hangzhou, Zhejiang, Peoples R China

来源：

SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE | 2024年 / 70卷 / 01期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

Semen quality; lifestyle; occupational exposure; green tea; overweight; alcohol consumption; ALCOHOL INTAKE; OXIDATIVE STRESS; SPERM DNA; CONSUMPTION; INFERTILITY; PARAMETERS; IMPACT;

D O I：

10.1080/19396368.2024.2357348

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

The incidence of male infertility (MI) is rising annually. However, the lifestyle and occupational exposure factors contributing to MI remain incompletely understood. This study explored the effects of self-reported lifestyle and occupational exposure factors on semen quality. Among 1060 subjects invited to participate, 826 were eligible. The participants' general characteristics, lifestyle, and occupational exposure factors were collected immediately before or after semen evaluation through an online questionnaire. Initially, univariate analysis was used to investigate the relationship between the abovementioned factors and semen quality. The results indicated significant associations between low semen quality and various factors, including age, BMI, infertility type and duration, abstinence time, semen and sperm parameters, smoking, alcohol consumption, irregular sleep habits, and frequent exposure to high temperatures and chemicals at work (p < 0.05). Then, multivariate analysis was conducted to identify factors independently associated with low semen quality. Adjustment for relevant confounders was achieved by including factors with a p-value < 0.25 from univariate analyses as covariates in the binomial and ordered logistic regression models. The results suggested that alcohol consumption was a positive factor for sperm concentration (odds ratio [OR] = 0.60; 95% confidence interval [CI] = 0.36-0.99; p = 0.045). The groups with a BMI >= 24 and <28 kg/m(2) showed a significant decrease in sperm progressive motility when compared to the reference group (BMI < 24 kg/m(2)) (OR = 0.63; 95% CI = 0.46-0.87, p = 0.005). In addition, the groups that drank green tea <1 time/week (OR = 1.52, 95% CI = 1.05-2.2) and 1-4 times/week (OR = 1.61, 95% CI = 1.02-2.54) exhibited significantly increased sperm DFI values compared with the group that drank green tea 5-7 times/week. In conclusion, these findings underscore the importance of maintaining a normal weight and regularly consuming green tea for men.

引用

页码：150 / 163

页数：14

共 40 条

[1] Supplementation of green tea extract (GTE) in extender improves structural and functional characteristics, total antioxidant capacity and in vivo fertility of buffalo (Bubalus bubalis) bull spermatozoa [J].