Diagnostic Role of FDG PET/CT in Pediatric Patients With Chronic Recurrent Multifocal Osteomyelitis

被引:1
作者
Xu, Yanfeng [1 ]
Wang, Guanyun [1 ]
Wang, Yu [1 ]
Wang, Wei [1 ]
Kan, Ying [1 ]
Yang, Jigang [1 ]
机构
[1] Capital Med Univ, Beijing Friendship Hosp, Dept Nucl Med, 95 Yong An Rd, Beijing 100050, Peoples R China
基金
中国国家自然科学基金;
关键词
FDG PET/CT; chronic recurrent multifocal osteomyelitis; CRMO; pediatric; diagnosis; CHRONIC NONBACTERIAL OSTEOMYELITIS; F-18-FDG PET/CT; INFECTION; BONE; PATHOGENESIS; TOMOGRAPHY;
D O I
10.1097/RLU.0000000000005216
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PurposeChronic recurrent multifocal osteomyelitis (CRMO), or chronic nonbacterial osteomyelitis, is difficult to diagnose. The accurate diagnosis of CRMO relies on comprehensive imaging examinations because of its multifocal nature. In this regard, 18F-FDG PET/CT has demonstrated significant utility in inflammatory diseases. This study tries to determine the value of FDG PET/CT in the evaluation of CRMO.Patients and MethodsWe retrospectively collected imaging data from pediatric CRMO patients who underwent FDG PET/CT scans. Lesions exhibiting abnormal metabolism with/without structural abnormalities on FDG PET/CT were identified as CRMO lesions, and their location and SUVmax were recorded.ResultsA total of 21 pediatric patients with CRMO were included in this study. The median age at diagnosis was 9.4 years. Total 131 foci of abnormal activity were identified using FDG PET/CT imaging. The distribution pattern showed a higher prevalence of lower limbs and pelvis involvement. Among all identified lesions, abnormalities were detected on both PET and CT images of 93 lesions, whereas exclusively positive findings on 18F-FDG PET alone were observed for 38 of them.ConclusionsOur study findings suggest a higher prevalence of lesions in the bones of the lower limbs and pelvis among children with CRMO. Compared with CT scans, FDG PET exhibits superior sensitivity in detecting these lesions.
引用
收藏
页码:536 / 539
页数:4
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