Ventricular Tachycardia Ablation Endpoints Moving Beyond Noninducibility

被引：4

作者：

Santangeli, Pasquale ^{[1
,2
]}

Higuchi, Koji ^{[1
]}

Sroubek, Jakub ^{[1
]}

机构：

[1] Cleveland Clin, Dept Cardiovasc Med, Sect Cardiac Pacing & Electrophysiol, Cleveland, OH USA

[2] Dept Cardiovasc Med, Sect Cardiac Pacing & Electrophysiol, J2-2,9500 Euclid Ave, Cleveland, OH 44195 USA

来源：

JACC-CLINICAL ELECTROPHYSIOLOGY | 2024年 / 10卷 / 05期

关键词：

catheter ablation; endpoints; substrate ablation; ventricular tachycardia; VT noninducibility; RADIOFREQUENCY CATHETER ABLATION; LIMITED-SUBSTRATE ABLATION; STRUCTURAL HEART-DISEASE; HIDDEN SLOW CONDUCTION; TO-DAY REPRODUCIBILITY; LONG-TERM OUTCOMES; SINUS RHYTHM; NONISCHEMIC CARDIOMYOPATHY; ISCHEMIC CARDIOMYOPATHY; MYOCARDIAL-INFARCTION;

D O I：

10.1016/j.jacep.2023.12.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In patients with structural heart disease and ventricular tachycardia (VT) undergoing catheter ablation, the response to programmed electrical stimulation (PES) at the end of the procedure has been traditionally used to evaluate the acute success and predict long-term outcomes. Although noninducibility at PES has been extensively investigated and validated in clinical trials and large multicenter registries, its performance in predicting long-term freedom from VT is suboptimal. In addition, PES has inherent limitations related to the in fluence of background antiarrhythmic drug therapy, periprocedural use of anesthesia, and the heterogeneity in PES protocols. The increased utilization of substrate -based ablation approaches that focus on ablation of abnormal electrograms identi fied with mapping in sinus or paced rhythm has been paralleled by a need for additional procedural endpoints beyond VT noninducibility at PES. This article critically appraises the relative merits and limitations of different procedural endpoints according to different ablation techniques for catheter ablation of scar -related VT. (J Am Coll Cardiol EP 2024;10:981 -999) (c) 2024 by the American College of Cardiology Foundation.

引用

页码：981 / 999

页数：19

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