Palladium supported on alumina as a highly active heterogeneous catalyst for direct arylation of 6-substituted imidazo[2,1-b]thiadiazole via C-H bond activation reaction

被引：1

作者：

Pouramiri, Behjat ^{[1
]}

Hadadianpour, Elahe ^{[2
]}

Saghebi, Soroosh ^{[3
]}

机构：

[1] Qom Univ Technol, Fac Sci, Dept Chem, Qom 37195, Iran

[2] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

[3] Univ Tehran, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2024年 / 150卷

关键词：

Imidazo[2,1-b]thiazole; C-H bond activation; Green synthesis; Heterogeneous; Microwave irradiation; Regioselective reaction; ELECTRON-RICH OLEFINS; CHEMISTRY; EFFICIENT; AGENTS;

D O I：

10.1016/j.tetlet.2024.155286

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fast, atom-economical, phosphine-free, and eco-friendly microwave-irradiated reactions permitting the "green synthesis" of 5,6-disubstituted imidazo[2,1-b]thiadiazole derivatives using heterogeneous palladium catalyst in triethylammonium 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetate ([Et3NH][Sac-CH3CO2]) ionic liquid via CH bond activation reaction of 6-substituted imidazo[2,1-b]thiadiazole derivatives, are reported. This method provides a straightforward route to a wide variety of substituted imidazo[2,1-b]thiadiazoles and has the advantages of reusability of the heterogeneous catalyst, simple methodology, high yields, and easy work-up.

引用

页数：4