Endothelin-1 promotes perivascular adipose tissue dysfunction in obese mice via Nrf2 downregulation and oxidative stress

被引：0
|
作者：
Tostes, Rita [1 ]
da Costa, Rafael Menezes [1 ,2 ]
Lima, Anna [1 ]
Rodrigues, Daniel [1 ]
Machado, Mirele [1 ]
Oliveira-Neto, Jose Teles [1 ]
Bressan, Alecsander [1 ]
Pedersoli, Carina [1 ]
Silva-Neto, Julio [1 ]
Barros, Paula [1 ]
机构：
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Pharmacol, Ribeirao Preto, Brazil
[2] Fed Univ Jatai, Hlth Sci Acad Unit, Jatai, Brazil
来源：
CLINICAL SCIENCE | 2024年 / 138卷
关键词：
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页数：107
相关论文
共 50 条
  • [1] Endothelin-1 promotes perivascular adipose tissue dysfunction in obese mice via Nrf2 downregulation and oxidative stress
    Tostes, Rita
    da Costa, Rafael Menezes
    Lima, Anna
    Rodrigues, Daniel
    Machado, Mirele
    Oliveira-Neto, Jose Teles
    Bressan, Alecsander
    Pedersoli, Carina
    Silva-Neto, Julio
    Barros, Paula
    CLINICAL SCIENCE, 2024, 138 : A27 - A27
  • [2] Adipose extracellular signal-regulated kinase 2 protected from endothelial dysfunction and the oxidative stress of perivascular adipose tissue in obese mice
    Osaki, A.
    Sato, Y.
    Endo, S.
    Ito, K.
    Kagami, K.
    Yumila, Y.
    Ishinoda, Y.
    Toya, T.
    Ido, Y.
    Namba, T.
    Adachi, T.
    EUROPEAN HEART JOURNAL, 2020, 41 : 3822 - 3822
  • [3] Ameliorating Oxidative Stress-Aggravated Adipose Tissue Senescence by Sesamol in Aged Obese Mice via Nrf2/p38MAPK Signaling
    Tang, Yongyan
    Zheng, Wenya
    Chen, Jingfang
    Xie, Yan
    Yang, Jinxin
    Wang, Zhipeng
    Qin, Hong
    PLANT FOODS FOR HUMAN NUTRITION, 2025, 80 (01)
  • [4] Sirtuin1 dysfunction in perivascular adipose tissue of diet-induced obese mice
    Xia, N.
    Reifenberg, G.
    Schirra, C.
    Li, H.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2020, 393 (SUPPL 1) : 67 - 67
  • [5] Periadventitial Adipose Tissue Promotes Endothelial Dysfunction via Oxidative Stress in Diet-Induced Obese C57BI/6 Mice
    Ketonen, Juha
    Shi, Jin
    Martonen, Essi
    Mervaala, Eero
    CIRCULATION JOURNAL, 2010, 74 (07) : 1479 - 1487
  • [6] Endothelin-1 Receptor Antagonism Attenuates Increased Uncoupling Protein-1 in Brown Adipose Tissue of Obese Mice
    Mills, Megumi
    Miller, Caroline
    Wilson, Natalie
    Speed, Joshua
    PHYSIOLOGY, 2024, 39
  • [7] Downregulation of Nrf2 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Aged Rats by Sensitizing Oxidative Stress and Neuroinflammation
    Li L.
    Meng F.
    Li D.
    Oxidative Medicine and Cellular Longevity, 2023, 2023
  • [8] Endothelin-1, Oxidative Stress and Vascular Dysfunction in Alzheimer's Disease
    Love, Seth
    Palmer, Jen
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2012, 71 (06): : 550 - 550
  • [9] Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1
    Wu, RQ
    Dong, WF
    Zhou, M
    Cui, XX
    Simms, HH
    Wang, P
    CARDIOVASCULAR RESEARCH, 2005, 68 (02) : 318 - 326
  • [10] Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway
    Yang, Chang-Sheng
    Guo, Xiao-Shuang
    Yue, Ying-Ying
    Wang, Yu
    Jin, Xiao-Lei
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
12345