Tubulointerstitial nephritis with storiform fibrosis in a patient with angioimmunoblastic T-cell lymphoma

被引：0

作者：

Fukuda, Haruka ^{[1
,2
]}

Kitamura, Mineaki ^{[1
,2
]}

Sawase, Atsushi ^{[1
,2
]}

Uramatsu, Tadashi ^{[1
,3
]}

Yamashita, Hiroshi ^{[1
,2
]}

Tsushima, Hideki ^{[4
]}

Irie, Junji ^{[5
]}

Katafuchi, Eisuke ^{[6
]}

Kato, Seiya ^{[7
]}

Takeuchi, Mai ^{[8
]}

Ohshima, Koichi ^{[8
]}

Nakayama, Toshiyuki ^{[6
]}

Mukae, Hiroshi ^{[9
]}

Nishino, Tomoya ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Nephrol, 1-7-1 Sakamoto, Nagasaki 8528501, Japan

[2] Nagasaki Harbor Med Ctr, Dept Nephrol, Nagasaki, Japan

[3] Nijigaoka Hosp, Dept Nephrol, Nagasaki, Japan

[4] Nagasaki Harbor Med Ctr, Dept Hematol, Nagasaki, Japan

[5] Nagasaki Harbor Med Ctr, Dept Pathol, Nagasaki, Japan

[6] Univ Occupat & Environm Hlth, Sch Med, Dept Pathol, Kitakyushu, Japan

[7] Saiseikai Fukuoka Gen Hosp, Div Pathol, Fukuoka, Japan

[8] Kurume Univ, Dept Pathol, Kurume, Japan

[9] Nagasaki Univ, Grad Sch Biomed Sci, Dept Resp Med, Nagasaki, Japan

来源：

CEN CASE REPORTS | 2025年 / 14卷 / 01期

关键词：

Angioimmunoblastic T-cell lymphoma; Interstitial nephritis; Storiform fibrosis; Follicular helper T (Tfh) cells; LYMPHADENOPATHY;

D O I：

10.1007/s13730-024-00901-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of an angioimmunoblastic T-cell lymphoma (AITL) and tubulointerstitial nephritis with storiform fibrosis in a 76-year-old man. The patient exhibited lymphadenopathy, polyclonal hypergammaglobulinemia, and renal dysfunction and was diagnosed with AITL on the basis of lymph node biopsy findings. The serum IgG4 level was highly elevated. Renal biopsy revealed IgG4-positive plasma cells and storiform fibrosis without infiltration of AITL, and the findings indicated IgG4-related kidney disease (IgG4-RKD). Following THPCOP therapy for AITL, the renal function improved. While diagnosing IgG4-RKD in a patient with AITL poses challenges, follicular helper T cell involvement appeared crucial in AITL and renal tubulointerstitial lesions in this case.

引用

页码：39 / 46

页数：8

共 50 条

[41] A Case of Angioimmunoblastic T-Cell Lymphoma Presenting as Airway Obstruction
Saxena, Akshat
Amal, Tanya
Khillan, Ratesh
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S400 - S400
[42] Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T-cell lymphoma: A case report
Yamamoto, Gaku
Takamura, Kei
Ishida, Yuriko
Sato, Yuma
Sinozaki, Ayuka
Kikuchi, Hajime
Yamamoto, Makoto
Kobayashi, Hajime
Hirose, Naoki
Kikuchi, Keisuke
RESPIROLOGY CASE REPORTS, 2022, 10 (04):
[43] Primary Cutaneous Follicular Helper T-cell Lymphoma Treated with Allogeneic Bone Marrow Transplantation: Immunohistochemical Comparison with Angioimmunoblastic T-cell Lymphoma
Ohmatsu, Hanako
Sugaya, Makoto
Fujita, Hideki
Kadono, Takafumi
Sato, Shinichi
ACTA DERMATO-VENEREOLOGICA, 2014, 94 (01) : 54 - 57
[44] Angioimmunoblastic T-Cell Lymphoma Mimicking Diffuse Large B-Cell Lymphoma
Ellis, Carolyn
Ramirez, James
LaFond, Ann Ammond
CUTIS, 2018, 102 (03): : 173 - 176
[45] Expression of Master Regulators of T-cell, Helper T-cell and Follicular Helper T-cell Differentiation in Angioimmunoblastic T-cell Lymphoma
Matsumoto, Yosuke
Nagoshi, Hisao
Yoshida, Mihoko
Kato, Seiichi
Kuroda, Junya
Shimura, Kazuho
Kaneko, Hiroto
Horiike, Shigeo
Nakamura, Shigeo
Taniwaki, Masafumi
INTERNAL MEDICINE, 2017, 56 (21) : 2851 - 2856
[46] Advances in the pathogenesis and therapeutic strategies of angioimmunoblastic T-cell lymphoma
Zhang, Qingyang
Yin, Le
Lai, Qinqiao
Zhao, Yan
Peng, Hongling
CLINICAL AND EXPERIMENTAL MEDICINE, 2023, 23 (08) : 4219 - 4235
[47] Identification of autofluorescent cells in human angioimmunoblastic T-cell lymphoma
Igor Buchwalow
Dmitri Atiakshin
Vera Samoilova
Werner Boecker
Markus Tiemann
Histochemistry and Cell Biology, 2018, 149 : 169 - 177
[48] Clinical manifestation of angioimmunoblastic T-cell lymphoma with exuberant plasmacytosis
Hisao Nagoshi
Junya Kuroda
Tsutomu Kobayashi
Saori Maegawa
Yoshiaki Chinen
Miki Kiyota
Ryuko Nakayama
Shinsuke Mizutani
Yuji Shimura
Mio Yamamoto-Sugitani
Yosuke Matsumoto
Shigeo Horiike
Masafumi Taniwaki
International Journal of Hematology, 2013, 98 : 366 - 374
[49] Clinical manifestation of angioimmunoblastic T-cell lymphoma with exuberant plasmacytosis
Nagoshi, Hisao
Kuroda, Junya
Kobayashi, Tsutomu
Maegawa, Saori
Chinen, Yoshiaki
Kiyota, Miki
Nakayama, Ryuko
Mizutani, Shinsuke
Shimura, Yuji
Yamamoto-Sugitani, Mio
Matsumoto, Yosuke
Horiike, Shigeo
Taniwaki, Masafumi
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2013, 98 (03) : 366 - 374
[50] Epigenetic focus on angioimmunoblastic T-cell lymphoma: pathogenesis and treatment
Tari, Gamze
Lemonnier, Francois
Morschhauser, Franck
CURRENT OPINION IN ONCOLOGY, 2021, 33 (05) : 400 - 405

← 1 2 3 4 5 →