Tubulointerstitial nephritis with storiform fibrosis in a patient with angioimmunoblastic T-cell lymphoma

被引：0

作者：

Fukuda, Haruka ^{[1
,2
]}

Kitamura, Mineaki ^{[1
,2
]}

Sawase, Atsushi ^{[1
,2
]}

Uramatsu, Tadashi ^{[1
,3
]}

Yamashita, Hiroshi ^{[1
,2
]}

Tsushima, Hideki ^{[4
]}

Irie, Junji ^{[5
]}

Katafuchi, Eisuke ^{[6
]}

Kato, Seiya ^{[7
]}

Takeuchi, Mai ^{[8
]}

Ohshima, Koichi ^{[8
]}

Nakayama, Toshiyuki ^{[6
]}

Mukae, Hiroshi ^{[9
]}

Nishino, Tomoya ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Nephrol, 1-7-1 Sakamoto, Nagasaki 8528501, Japan

[2] Nagasaki Harbor Med Ctr, Dept Nephrol, Nagasaki, Japan

[3] Nijigaoka Hosp, Dept Nephrol, Nagasaki, Japan

[4] Nagasaki Harbor Med Ctr, Dept Hematol, Nagasaki, Japan

[5] Nagasaki Harbor Med Ctr, Dept Pathol, Nagasaki, Japan

[6] Univ Occupat & Environm Hlth, Sch Med, Dept Pathol, Kitakyushu, Japan

[7] Saiseikai Fukuoka Gen Hosp, Div Pathol, Fukuoka, Japan

[8] Kurume Univ, Dept Pathol, Kurume, Japan

[9] Nagasaki Univ, Grad Sch Biomed Sci, Dept Resp Med, Nagasaki, Japan

来源：

CEN CASE REPORTS | 2025年 / 14卷 / 01期

关键词：

Angioimmunoblastic T-cell lymphoma; Interstitial nephritis; Storiform fibrosis; Follicular helper T (Tfh) cells; LYMPHADENOPATHY;

D O I：

10.1007/s13730-024-00901-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of an angioimmunoblastic T-cell lymphoma (AITL) and tubulointerstitial nephritis with storiform fibrosis in a 76-year-old man. The patient exhibited lymphadenopathy, polyclonal hypergammaglobulinemia, and renal dysfunction and was diagnosed with AITL on the basis of lymph node biopsy findings. The serum IgG4 level was highly elevated. Renal biopsy revealed IgG4-positive plasma cells and storiform fibrosis without infiltration of AITL, and the findings indicated IgG4-related kidney disease (IgG4-RKD). Following THPCOP therapy for AITL, the renal function improved. While diagnosing IgG4-RKD in a patient with AITL poses challenges, follicular helper T cell involvement appeared crucial in AITL and renal tubulointerstitial lesions in this case.

引用

页码：39 / 46

页数：8

共 50 条

[31] Angioimmunoblastic T-cell lymphoma: A relatively common type of T-cell lymphoma in Sjogren's syndrome
Saito, M
Fukuda, T
Shiohara, T
Homori, M
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2005, 23 (06) : 888 - 890
[32] Angioimmunoblastic T-cell lymphoma with dual genotype of TCR and IgH genes
Aung, Naing Ye
Ohtake, Hiroya
Iwaba, Akiko
Kato, Tomoya
Ohe, Rintaro
Tajima, Katsushi
Nagase, Teruaki
Yamakawa, Mitsunori
PATHOLOGY RESEARCH AND PRACTICE, 2011, 207 (05) : 317 - 321
[33] Clinicopathologic Characteristics of Angioimmunoblastic T-Cell Lymphoma: Analysis of the International Peripheral T-Cell Lymphoma Project
Federico, Massimo
Rudiger, Thomas
Bellei, Monica
Nathwani, Bharat N.
Luminari, Stefano
Coiffier, Bertrand
Harris, Nancy L.
Jaffe, Elaine S.
Pileri, Stefano A.
Savage, Kerry J.
Weisenburger, Dennis D.
Armitage, James O.
Mounier, Nicholas
Vose, Julie M.
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (02) : 240 - 246
[34] Detection of immunoglobulin and T-cell receptor gene rearrangements in angioimmunoblastic T-cell lymphoma
Zhu, Wei
He, Qiu-Yan
Lu, Can
Fu, Chun-Yan
Zhou, Jian-Hua
Liu, Shuang
Tao, Yong-Guang
Xiao, De-Sheng
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2018, 11 (05): : 2642 - 2653
[35] Extranodal Marginal Zone Lymphoma-like Presentations of Angioimmunoblastic T-Cell Lymphoma: A T-Cell Lymphoma Masquerading as a B-Cell Lymphoproliferative Disorder
Kaffenberger, Benjamin
Haverkos, Brad
Tyler, Kelly
Wong, Henry K.
Porcu, Pierluigi
Gru, Alejandro Ariel
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2015, 37 (08) : 604 - 613
[36] Effects of stem cell transplantation in patients with peripheral T-cell lymphoma not otherwise specified and angioimmunoblastic T-cell lymphoma
Yamasaki, Satoshi
Yoshida, Shuro
Kato, Koji
Choi, Ilseung
Imamura, Yutaka
Kohno, Kentaro
Henzan, Hideho
Tanimoto, Kazuki
Ogawa, Ryosuke
Suehiro, Youko
Miyamoto, Toshihiro
Eto, Tetsuya
Ohshima, Koichi
Akashi, Koichi
Iwasaki, Hiromi
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2020, 112 (01) : 74 - 83
[37] Angioimmunoblastic T-Cell Lymphoma: Report on 282 Cases from the Prospective International T-Cell Lymphoma Project
Skrypets, Tetiana
Civallero, Monica
Manni, Martina
Pileri, Stefano
Weisenburger, Dennis D.
Ko, Young Hyeh
Inghirami, Giorgio
Bargetzi, Mario
Gabus, Raul
Bobillo Varela, Sabela
Horwitz, Steven M.
Pavlovsky, Astrid
Thieblemont, Catherine
De Souza, Carmino Antonio
Milone, Jorge
Kim, Won Seog Kim
Montoto, Silvia
Carson, Kenneth
Vose, Julie M.
Federico, Massimo
Advani, Ranjana H.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 : S253 - S254
[38] Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma
Troxell, ML
Schwartz, EJ
van de Ruin, M
Ross, DT
Warnke, RA
Higgins, JP
Natkunam, Y
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2005, 13 (04) : 297 - 303
[39] Effects of stem cell transplantation in patients with peripheral T-cell lymphoma not otherwise specified and angioimmunoblastic T-cell lymphoma
Satoshi Yamasaki
Shuro Yoshida
Koji Kato
Ilseung Choi
Yutaka Imamura
Kentaro Kohno
Hideho Henzan
Kazuki Tanimoto
Ryosuke Ogawa
Youko Suehiro
Toshihiro Miyamoto
Tetsuya Eto
Koichi Ohshima
Koichi Akashi
Hiromi Iwasaki
International Journal of Hematology, 2020, 112 : 74 - 83
[40] A suspicion of chikungunya leading to a diagnosis of angioimmunoblastic T-cell lymphoma
Braiteh, Fadi
Parikh, Ankur
McLaughlin, Peter
ACTA ONCOLOGICA, 2009, 48 (04) : 624 - 628

← 1 2 3 4 5 →