Surface-Enhanced Raman Scattering Nanosensing and Imaging in Neuroscience

被引:4
作者
Boudries, Ryma [1 ,2 ]
Williams, Hannah [1 ,2 ]
Paquereau-Gaboreau, Soraya [1 ,2 ,3 ,4 ]
Bashir, Saba [1 ,2 ]
Jodaylami, Maryam Hojjat [1 ,2 ]
Chisanga, Malama [1 ,2 ]
Trudeau, Louis-Eric [3 ,4 ]
Masson, Jean-Francois [1 ,2 ,4 ]
机构
[1] Univ Montreal, Inst Courtois, QCAM, Dept Chem, Montreal, PQ H3C 3J7, Canada
[2] Univ Montreal, RQMP, Montreal, PQ H3C 3J7, Canada
[3] Univ Montreal, Fac Med, Dept Pharmacol & Physiol, Dept Neurosci, Montreal, PQ H3C 3J7, Canada
[4] Univ Montreal, Ctr Interdisciplinary Res Brain & Learning CIRCA, Neural Signalling & Circuitry Res Grp SNC, Montreal, PQ H3C 3J7, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Surface-enhanced Raman scattering; nanosensors; plasmon; nanoparticles; neurotransmitters; neurodegenerative diseases; brain; IN-VIVO; ALZHEIMERS-DISEASE; GOLD NANOPARTICLES; SPECTROSCOPY DETECTION; QUANTITATIVE DETECTION; LIQUID-CHROMATOGRAPHY; AMPLIFICATION ASSAY; CEREBROSPINAL-FLUID; SENSITIVE DETECTION; PLASMON RESONANCE;
D O I
10.1021/acsnano.4c05200
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Monitoring neurochemicals and imaging the molecular content of brain tissues in vitro, ex vivo, and in vivo is essential for enhancing our understanding of neurochemistry and the causes of brain disorders. This review explores the potential applications of surface-enhanced Raman scattering (SERS) nanosensors in neurosciences, where their adoption could lead to significant progress in the field. These applications encompass detecting neurotransmitters or brain disorders biomarkers in biofluids with SERS nanosensors, and imaging normal and pathological brain tissues with SERS labeling. Specific studies highlighting in vitro, ex vivo, and in vivo analysis of brain disorders using fit-for-purpose SERS nanosensors will be detailed, with an emphasis on the ability of SERS to detect clinically pertinent levels of neurochemicals. Recent advancements in designing SERS-active nanomaterials, improving experimentation in biofluids, and increasing the usage of machine learning for interpreting SERS spectra will also be discussed. Furthermore, we will address the tagging of tissues presenting pathologies with nanoparticles for SERS imaging, a burgeoning domain of neuroscience that has been demonstrated to be effective in guiding tumor removal during brain surgery. The review also explores future research applications for SERS nanosensors in neuroscience, including monitoring neurochemistry in vivo with greater penetration using surface-enhanced spatially offset Raman scattering (SESORS), near-infrared lasers, and 2-photon techniques. The article concludes by discussing the potential of SERS for investigating the effectiveness of therapies for brain disorders and for integrating conventional neurochemistry techniques with SERS sensing.
引用
收藏
页码:22620 / 22647
页数:28
相关论文
共 293 条
  • [1] Recording Neural Activity Based on Surface Plasmon Resonance by Optical Fibers-A Computational Analysis
    Abedini, Mitra
    Tekieh, Tahereh
    Sasanpour, Pezhman
    [J]. FRONTIERS IN COMPUTATIONAL NEUROSCIENCE, 2018, 12
  • [2] Aizpurua J, 2017, FARADAY DISCUSS, V205, P291, DOI [10.1039/c7fd90088k, 10.1039/C7FD90088K]
  • [3] Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics
    Akerboom, Jasper
    Calderon, Nicole Carreras
    Tian, Lin
    Wabnig, Sebastian
    Prigge, Matthias
    Tolo, Johan
    Gordus, Andrew
    Orger, Michael B.
    Severi, Kristen E.
    Macklin, John J.
    Patel, Ronak
    Pulver, Stefan R.
    Wardill, Trevor J.
    Fischer, Elisabeth
    Schueler, Christina
    Chen, Tsai-Wen
    Sarkisyan, Karen S.
    Marvin, Jonathan S.
    Bargmann, Cornelia I.
    Kim, Douglas S.
    Kugler, Sebastian
    Lagnado, Leon
    Hegemann, Peter
    Gottschalk, Alexander
    Schreiter, Eric R.
    Looger, Loren L.
    [J]. FRONTIERS IN MOLECULAR NEUROSCIENCE, 2013, 6
  • [4] Nanotools for Neuroscience and Brain Activity Mapping
    Alivisatos, A. Paul
    Andrews, Anne M.
    Boyden, Edward S.
    Chun, Miyoung
    Church, George M.
    Deisseroth, Karl
    Donoghue, John P.
    Fraser, Scott E.
    Lippincott-Schwartz, Jennifer
    Looger, Loren L.
    Masmanidis, Sotiris
    McEuen, Paul L.
    Nurmikko, Arto V.
    Park, Hongkun
    Peterka, Darcy S.
    Reid, Clay
    Roukes, Michael L.
    Scherer, Axel
    Schnitzer, Mark
    Sejnowski, Terrence J.
    Shepard, Kenneth L.
    Tsao, Doris
    Turrigiano, Gina
    Weiss, Paul S.
    Xu, Chris
    Yuste, Rafael
    Zhuang, Xiaowei
    [J]. ACS NANO, 2013, 7 (03) : 1850 - 1866
  • [5] The Brain Activity Map
    Alivisatos, A. Paul
    Chun, Miyoung
    Church, George M.
    Deisseroth, Karl
    Donoghue, John P.
    Greenspan, Ralph J.
    McEuen, Paul L.
    Roukes, Michael L.
    Sejnowski, Terrence J.
    Weiss, Paul S.
    Yuste, Rafael
    [J]. SCIENCE, 2013, 339 (6125) : 1284 - 1285
  • [6] Gold Nanoparticles-Based Barcode Analysis for Detection of Norepinephrine
    An, Jeung Hee
    Lee, Kwon-Jai
    Choi, Jeong-Woo
    [J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2016, 12 (02) : 357 - 365
  • [7] Surface-enhanced Raman spectroscopy detection of dopamine by DNA Targeting amplification assay in Parkisons's model
    An, Jeung Hee
    Choi, Dong-Kug
    Lee, Kwon-Jai
    Choi, Jeong-Woo
    [J]. BIOSENSORS & BIOELECTRONICS, 2015, 67 : 739 - 746
  • [8] Nanomedicine for Spontaneous Brain Tumors: A Companion Clinical Trial
    Arami, Hamed
    Patel, Chirag B.
    Madsen, Steven J.
    Dickinson, Peter J.
    Davis, Ryan M.
    Zeng, Yitian
    Sturges, Beverly K.
    Woolard, Kevin D.
    Habte, Frezghi G.
    Akin, Demir
    Sinclair, Robert
    Gambhir, Sanjiv S.
    [J]. ACS NANO, 2019, 13 (03) : 2858 - 2869
  • [9] Shape and Size Control of Substrate-Grown Gold Nanoparticles for Surface-Enhanced Raman Spectroscopy Detection of Chemical Analytes
    Ashley, Michael J.
    Bourgeois, Marc R.
    Murthy, Raghavendra R.
    Laramy, Christine R.
    Ross, Michael B.
    Naik, Rajesh R.
    Schatz, George C.
    Mirkin, Chad A.
    [J]. JOURNAL OF PHYSICAL CHEMISTRY C, 2018, 122 (04) : 2307 - 2314
  • [10] Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease monitoring
    Ashton, Nicholas J.
    Janelidze, Shorena
    Mattsson-Carlgren, Niklas
    Binette, Alexa Pichet
    Strandberg, Olof
    Brum, Wagner S.
    Karikari, Thomas K.
    Gonzalez-Ortiz, Fernando
    Di Molfetta, Guglielmo
    Meda, Francisco J.
    Jonaitis, Erin M.
    Koscik, Rebecca Langhough
    Cody, Karly
    Betthauser, Tobey J.
    Li, Yan
    Vanmechelen, Eugeen
    Palmqvist, Sebastian
    Stomrud, Erik
    Bateman, Randall J.
    Zetterberg, Henrik
    Johnson, Sterling C.
    Blennow, Kaj
    Hansson, Oskar
    [J]. NATURE MEDICINE, 2022, 28 (12) : 2555 - +