A positive take on negative selection for CAR-T manufacturing

被引:1
作者
Orentas, Rimas J. [1 ]
机构
[1] Caring Cross & Johns Hopkins Bloomberg Sch Publ Hl, 910 Clopper Rd Suite 200 S, Gaithersburg, MD 20892 USA
关键词
D O I
10.1016/j.omtm.2024.101218
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
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页数:2
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共 11 条
[1]   Ex vivo isolation protocols differentially affect the phenotype of human CD4+T cells [J].
Bernard, F ;
Jaleco, S ;
Dardalhon, V ;
Steinberg, M ;
Yssel, H ;
Noraz, N ;
Taylor, N ;
Kinet, S .
JOURNAL OF IMMUNOLOGICAL METHODS, 2002, 271 (1-2) :99-106
[2]   High-dimensional in situ proteomics imaging to assess γδ T cells in spatial biology [J].
Herold, Nicola ;
Bruhns, Matthias ;
Babaei, Sepideh ;
Spreuer, Janine ;
Castagna, Arianna ;
Yurttas, Can ;
Scheuermann, Sophia ;
Seitz, Christian ;
Ruf, Benjamin ;
Koenigsrainer, Alfred ;
Jurmeister, Philipp ;
Loeffler, Markus W. ;
Claassen, Manfred ;
Wistuba-Hamprecht, Kilian .
JOURNAL OF LEUKOCYTE BIOLOGY, 2024, 115 (04) :750-759
[3]   Dissecting the cellular components of ex vivo γδ T cell expansions to optimize selection of potent cell therapy donors for neuroblastoma immunotherapy trials [J].
Jonus, Hunter C. ;
Burnham, Rebecca E. ;
Ho, Andrew ;
Pilgrim, Adeiye A. ;
Shim, Jenny ;
Doering, Christopher B. ;
Spencer, H. Trent ;
Goldsmith, Kelly C. .
ONCOIMMUNOLOGY, 2022, 11 (01)
[4]  
Mathioudaki A., 2024, Blood. blood
[5]   Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell [J].
Ruella, Marco ;
Xu, Jun ;
Barrett, David M. ;
Fraietta, Joseph A. ;
Reich, Tyler J. ;
Ambrose, David E. ;
Klichinsky, Michael ;
Shestova, Olga ;
Patel, Prachi R. ;
Kulikovskaya, Irina ;
Nazimuddin, Farzana ;
Bhoj, Vijay G. ;
Orlando, Elena J. ;
Fry, Terry J. ;
Bitter, Hans ;
Maude, Shannon L. ;
Levine, Bruce L. ;
Nobles, Christopher L. ;
Bushman, Frederic D. ;
Young, Regina M. ;
Scholler, John ;
Gill, Saar I. ;
June, Carl H. ;
Grupp, Stephan A. ;
Lacey, Simon F. ;
Melenhorst, J. Joseph .
NATURE MEDICINE, 2018, 24 (10) :1499-+
[6]   CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial [J].
Shah, Nirali N. ;
Highfill, Steven L. ;
Shalabi, Haneen ;
Yates, Bonnie ;
Jin, Jianjian ;
Wolters, Pamela L. ;
Ombrello, Amanda ;
Steinberg, Seth M. ;
Martin, Staci ;
Delbrook, Cindy ;
Hoffman, Leah ;
Little, Lauren ;
Ponduri, Anusha ;
Qin, Haiying ;
Qureshi, Haris ;
Dulau-Florea, Alina ;
Salem, Dalia ;
Wang, Hao-Wei ;
Yuan, Constance ;
Stetler-Stevenson, Maryalice ;
Panch, Sandhya ;
Tran, Minh ;
Mackall, Crystal L. ;
Stroncek, David F. ;
Fry, Terry J. .
JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (17) :1938-+
[7]   Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and yδ T cell output [J].
Song, Hannah W. ;
Benzaoui, Mehdi ;
Dwivedi, Alka ;
Underwood, Sarah ;
Shao, Lipei ;
Achar, Sooraj ;
Posarac, Vesna ;
Remley, Victoria A. ;
Prochazkova, Michaela ;
Cai, Yihua ;
Jin, Ping ;
Somerville, Robert P. ;
Stroncek, David F. ;
Altan-Bonnet, Gregoire ;
Shah, Nirali N. ;
Chien, Christopher D. ;
Taylor, Naomi ;
Highfill, Steven L. .
MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2024, 32 (01)
[8]   Myeloid cells in peripheral blood mononuclear cell concentrates inhibit the expansion of chimeric antigen receptor T cells [J].
Stroncek, David F. ;
Ren, Jiaqiang ;
Lee, Daniel W. ;
Minh Tran ;
Frodigh, Sue Ellen ;
Sabatino, Marianna ;
Khuu, Hanh ;
Merchant, Melinda S. ;
Mackall, Crystal L. .
CYTOTHERAPY, 2016, 18 (07) :893-901
[9]   Gamma/delta T cells as cellular vehicles for anti-tumor immunity [J].
Wang, Chelsia Qiuxia ;
Lim, Pei Yu ;
Tan, Andy Hee-Meng .
FRONTIERS IN IMMUNOLOGY, 2024, 14
[10]   A simple and effective method to purify and activate T cells for successful generation of chimeric antigen receptor T (CAR-T) cells from patients with high monocyte count [J].
Wang, Haiying ;
Tsao, Shih-Ting ;
Gu, Mingyuan ;
Fu, Chengbing ;
He, Feng ;
Li, Xiu ;
Zhang, Mian ;
Li, Na ;
Hu, Hong-Ming .
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 20 (01)