Mechanical Aortic Valve Thrombosis During Anticoagulation Using Oral Rivaroxaban: A Case Report

被引：0

作者：

Kinoshita, Ryoji ^{[1
]}

Watanabe, Taiju ^{[1
]}

Matsumoto, Ryumon ^{[1
]}

Hirooka, Kazunobu ^{[1
]}

机构：

[1] Tsuchiura Kyodo Gen Hosp, Cardiovasc Surg, Tsuchiura, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 07期

关键词：

rivaroxaban; warfarin; aortic valve replacement; direct oral anticoagulant; thrombosed mechanical aortic valve; VALVULAR HEART-DISEASE; ATRIAL-FIBRILLATION; WARFARIN; DABIGATRAN; MANAGEMENT; APIXABAN; EDOXABAN;

D O I：

10.7759/cureus.65007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Direct oral anticoagulants (DOACs) are widely used in cardiovascular medicine. Although rivaroxaban has potential benefits for anticoagulation in certain contexts, DOACs remain contraindicated in patients with mechanical heart valves. This case report highlights the life-threatening risks of rivaroxaban use in patients with mechanical aortic valves, underscoring the lack of proven efficacy and the necessity of adhering to established anticoagulation protocols with warfarin for this patient population. Here, we report a case of a 65-year-old man who had previously undergone aortic valve replacement and developed a thrombus in the mechanical aortic valve six months after switching from warfarin to rivaroxaban. The patient experienced a sudden loss of consciousness and chest discomfort. Echocardiography revealed a thrombus in the valve requiring urgent reoperation and replacement with a bioprosthetic valve. The postoperative recovery was uneventful.

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