Deproteinized bovine bone in association with guided tissue regeneration or enamel matrix derivatives procedures in aggressive periodontitis patients: a 1-year retrospective study

ObjectivesTo retrospectively evaluate and compare two regenerative periodontal procedures in young individuals with aggressive periodontitis (AgP). MethodsThirty-two patients aged 14-25years (meanSD 19.35.7) were diagnosed as having AgP with multiple intra-bony defects (IBDs) and treated by one of two regenerative modalities of periodontal therapy: guided tissue regeneration (GTR) using deproteinized bone xenograft (DBX) particles and a resorbable membrane (the GTR group), or an application of enamel matrix derivatives (EMD) combined with DBX (the EMD/DBX group). Periodic monitoring of treated sites included recording of probing depth (PD), clinical attachment level (CAL) and gingival recession. Pre-treatment and 1-year post-operative findings were statistically analysed within and between groups. ResultsThe PD and CAL values decreased significantly with time, but not those between study groups. The mean pre-treatment and 1-year post-treatment PDs of the IBDs of the GTR group (n=16; sites=67) were 8.93 +/- 1.14mm and 3.58 +/- 0.50mm, respectively, and the mean CALs were 9.03 +/- 1.03mm and 4.16 +/- 0.53mm respectively. The mean PDs of the EMD/DBX group (n=16; sites=73) were 8.77 +/- 1.04mm and 3.61 +/- 0.36mm, respectively, and the mean CALS were 8.79 +/- 1.04mm and 3.77 +/- 0.22mm respectively (p<0.001 for all). ConclusionSurgical treatment of AgP patients by either GTR or by application of EMD/DBX yielded similarly successful clinical results at 1-year post-treatment.