Effects of Compound Danshen Dripping Pills in the Treatment of Angina Pectoris in Coronary Heart Disease: A Meta-Analysis

To explore the research effects of compound Danshen dripping pills on the changes of electrocardiogram and hemorheology in the treatment of angina pectoris in coronary heart disease is the objective of the study. In this study we have collected papers from PubMed, Web of Science, Cochrane library, Google Scholar, China National Knowledge Infrastructure, Wanfang, Embase and virus protein domain database and the retrieval time limit is from the establishment of the database to May 2023. In this study we used ReviewManager 5.4 for meta-analysis. 9 studies were included here. In terms of various efficacy indicators, 8 studies clearly indicated that the clinical efficacy of the treatment group was better than that of the control group (relative risk=1.18, 95 % confidence interval: 1.10-1.26). Two of the studies measured the efficacy of electrocardiogram and the results showed that the treatment group had better electrocardiogram efficacy after compound Danshen dripping pills treatment (relative risk=1.39, 95 % confidence interval: 1.20-1.62). Three studies mentioned the frequency and duration of angina pectoris, all of which were significantly improved after compound Danshen dripping pills treatment (standardized mean difference=-1.35, 95 % confidence interval: -1.62 to -1.08, p<0.01) and (standardized mean difference=-2.15, 95 % confidence interval: -2.54 to -1.77, p<0.01); both high sensitivity c-reactive protein and endothelin were significantly decreased in the treatment group (standardized mean difference=-1.79, 95 % confidence interval: -2.18 to -1.40, p<0.01) and (standardized mean difference=-3.24, 95 % confidence interval -3.75 to -2.73, p<0.01). Two studies showed changes in hemorheology and the index of hemorheology in the treatment group was lower than that in the control group. The 9 included studies showed that compound Danshen dripping pills are safe and effective in treating patients with coronary heart disease and angina pectoris. Compared with conventional treatment alone, the clinical efficacy can be further improved using this.