SARS-CoV-2 Unmasks Type 1 Diabetes Mellitus With an Episode of Diabetic Ketoacidosis

被引：1

作者：

Halioti, Asimenia ^{[1
]}

Kitinou, Maria ^{[1
]}

Chalioti, Varvara-Maria ^{[2
]}

Chaliotis, Georgios ^{[1
]}

机构：

[1] Gen Hosp Chalkida, COVID 19 Clin, Chalkida 34100, Evia, Greece

[2] Gen Hosp Chalkida, Biochem Unit, Microbiol Lab, Chalkida, Evia, Greece

来源：

JOURNAL OF MEDICAL CASES | 2022年 / 13卷 / 09期

关键词：

Pandemic; Diabetic ketoacidosis; Type 1 diabetes mellitus; SARS-CoV-2; COVID-19; COVID-19;

D O I：

10.14740/jmc3963

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

During the severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) pandemic, coronavirus disease 2019 (COVID-19) has been significantly studied for its relationship with diabetes mellitus in general. Still, the association of SARS-CoV-2 infection with diabetic ketoacidosis (DKA) is more specific and warrants a meticulous investigational approach. In this case report, we present a 23 -year -old female who developed DKA as the first manifestation of SARS-CoV-2 infection. During hospitalization, the diagnosis of type 1 diabetes mellitus (T1DM) was made and the patient was treated successfully for the metabolic disorder and for SARS-CoV-2. The potential of SARSCoV-2 to induce DKA in type 1 diabetics is highlighted. We point out that DKA and COVID-19 may have similarities in clinical presentation when gastrointestinal features predominate. In addition, we describe mechanisms that have been hypothesized to explain the negative impact of SARS-CoV-2 on the endocrine pancreatic function.

引用

页码：432 / 437

页数：6

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