Advances in upconversion luminescence nanomaterial-based biosensor for virus diagnosis

被引:67
作者
Ma, Yingjin [1 ]
Song, Menglin [1 ]
Li, Lihua [1 ]
Lao, Xinyue [1 ]
Wong, Man-Chung [1 ]
Hao, Jianhua [1 ]
机构
[1] Hong Kong Polytech Univ, Dept Appl Phys, Hong Kong 999077, Peoples R China
来源
EXPLORATION | 2022年 / 2卷 / 06期
关键词
biosensor; luminescent or electric response; pathogen detection; upconversion nanoparticles (UCNPs); virus diagnosis; RESONANCE ENERGY-TRANSFER; AVIAN INFLUENZA-VIRUS; ULTRASENSITIVE DETECTION; UPCONVERTING PHOSPHOR; SENSITIVE DETECTION; GOLD NANORODS; ASSAY; NANOPARTICLES; IMMUNOASSAY; NANOPROBES;
D O I
10.1002/EXP.20210216
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Various infectious viruses have been posing a major threat to global public health, especially SARS-CoV-2, which has already claimed more than six million lives up to now. Tremendous efforts have been made to develop effective techniques for rapid and reliable pathogen detection. The unique characteristics of upconversion nanoparticles (UCNPs) pose numerous advantages when employed in biosensors, and they are a promising candidate for virus detection. Herein, this Review will discuss the recent advancement in the UCNP-based biosensors for virus and biomarkers detection. We summarize four basic principles that guide the design of UCNP-based biosensors, which are utilized with luminescent or electric responses as output signals. These strategies under fundamental mechanisms facilitate the enhancement of the sensitivity of UCNP-based biosensors. Moreover, a detailed discussion and benefits of applying UCNP in various virus bioassays will be presented. We will also address some obstacles in these detection techniques and suggest routes for progress in the field. These progressions will undoubtedly pose UCNP-based biosensors in a prominent position for providing a convenient, alternative approach to virus detection.
引用
收藏
页数:17
相关论文
共 102 条
[1]   FRET as a biomolecular research tool-understanding its potential while avoiding pitfalls [J].
Algar, W. Russ ;
Hildebrandt, Niko ;
Vogel, Steven S. ;
Medintz, Igor L. .
NATURE METHODS, 2019, 16 (09) :815-829
[2]   Functionalized upconversion nanoparticles: New strategy towards FRET-based luminescence bio-sensing [J].
Ansari, Anees A. ;
Thakur, Vijay K. ;
Chen, Guanying .
COORDINATION CHEMISTRY REVIEWS, 2021, 436
[3]   Bio-microarray fabrication techniques - A review [J].
Barbulovic-Nad, Irena ;
Lucente, Michael ;
Sun, Yu ;
Zhang, Mingjun ;
Wheeler, Aaron R. ;
Bussmann, Markus .
CRITICAL REVIEWS IN BIOTECHNOLOGY, 2006, 26 (04) :237-259
[4]   Luminescent Nanomaterials Doped with Rare Earth Ions and Prospects for Their Biomedical Applications (A Review) [J].
Bazhukova, I. N. ;
Pustovarov, V. A. ;
Myshkina, A. V. ;
Ulitko, M. V. .
OPTICS AND SPECTROSCOPY, 2020, 128 (12) :2050-2068
[5]   Quantitative real-time RT-PCR - a perspective [J].
Bustin, SA ;
Benes, V ;
Nolan, T ;
Pfaffl, MW .
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2005, 34 (03) :597-601
[6]   Optical biosensors: an exhaustive and comprehensive review [J].
Chen, Chen ;
Wang, Junsheng .
ANALYST, 2020, 145 (05) :1605-1628
[7]   A novel upconversion luminescence derived photoelectrochemical immunoassay: ultrasensitive detection to alpha-fetoprotein [J].
Chen, Xu ;
Xu, Wen ;
Jiang, Yandong ;
Pan, Gencai ;
Zhou, Donglei ;
Zhu, Jinyang ;
Wang, He ;
Chen, Cong ;
Li, Dongyu ;
Song, Hongwei .
NANOSCALE, 2017, 9 (42) :16357-16364
[8]   Optical biosensors [J].
Damborsky, Pavel ;
Svitel, Juraj ;
Katrlik, Jaroslav .
BIOSENSOR TECHNOLOGIES FOR DETECTION OF BIOMOLECULES, 2016, 60 (01) :91-100
[9]   Lanthanide Nanoparticles: From Design toward Bioimaging and Therapy [J].
Dong, Hao ;
Du, Shuo-Ren ;
Zheng, Xiao-Yu ;
Lyu, Guang-Ming ;
Sun, Ling-Dong ;
Li, Lin-Dong ;
Zhang, Pei-Zhi ;
Zhang, Chao ;
Yan, Chun-Hua .
CHEMICAL REVIEWS, 2015, 115 (19) :10725-10815
[10]   Dual-color upconversion fluorescence and aptamer-functionalized magnetic nanoparticles-based bioassay for the simultaneous detection of Salmonella Typhimurium and Staphylococcus aureus [J].
Duan, Nuo ;
Wu, Shijia ;
Zhu, Changqing ;
Ma, Xiaoyuan ;
Wang, Zhouping ;
Yu, Ye ;
Jiang, Yuan .
ANALYTICA CHIMICA ACTA, 2012, 723 :1-6