Arsenic sulfide triggers ferroptosis in hepatocellular carcinoma cells via TRPC6/GPX4 signaling

被引：1
|
作者：
Lu, Shumin
Cai, Yu
Zhu, Chuanying
Feng, Zhuowei
Chen, Shuxian
Chen, Siyu
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 06期
关键词：
D O I：
10.1158/1538-7445.AM2024-362
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
362
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Erianin triggers ferroptosis in colorectal cancer cells by facilitating the ubiquitination and degradation of GPX4
    Zheng, Yuting
    Zheng, Yinli
    Chen, Haipeng
    Tan, Xuanjing
    Zhang, Guiyu
    Kong, Muyan
    Jiang, Ruidi
    Yu, Hong
    Shan, Keyao
    Liu, Jiyao
    Zhang, Rong
    Liu, Zhongqiu
    Wu, Jinjun
    PHYTOMEDICINE, 2025, 139
  • [2] MDH2 Promotes Hepatocellular Carcinoma Growth Through Ferroptosis Evasion via Stabilizing GPX4
    Yu, Wenjia
    Li, Yingping
    Gao, Chengchang
    Li, Donglin
    Chen, Liangjie
    Dai, Bolei
    Yang, Haoying
    Han, Linfen
    Deng, Qinqin
    Bian, Xueli
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (21)
  • [3] Homocysteine induces ferroptosis in endothelial cells through the systemXc−/GPX4 signaling pathway
    Jiahao Shi
    Di Chen
    Zilin Wang
    Shaolin Li
    Shuying Zhang
    BMC Cardiovascular Disorders, 23
  • [4] GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis
    Wang, Qiujie
    Bin, Cheng
    Xue, Qiang
    Gao, Qingzhu
    Huang, Ailong
    Wang, Kai
    Tang, Ni
    CELL DEATH & DISEASE, 2021, 12 (05)
  • [5] GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis
    Qiujie Wang
    Cheng Bin
    Qiang Xue
    Qingzhu Gao
    Ailong Huang
    Kai Wang
    Ni Tang
    Cell Death & Disease, 12
  • [6] Targeting NFE2L2/GPX4 signaling pathway: Therapeutic potential of arsenic sulfide-induced ferroptosis in combating rhabdomyosarcoma
    Cai, Yu
    Lu, Shumin
    Zhu, Chuanying
    Kang, Ting
    Liu, Zhiyi
    Huang, Ruizhe
    Zhao, Yawei
    Chen, Siyu
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 143
  • [7] NeuroD1-GPX4 signaling leads to ferroptosis resistance in hepatocellular carcinoma
    Huang, Ping
    Duan, Wei
    Ruan, Cao
    Wang, Lingxian
    Hosea, Rendy
    Wu, Zheng
    Zeng, Jianting
    Wu, Shourong
    Kasim, Vivi
    PLOS GENETICS, 2023, 19 (12):
  • [8] Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/STAT3/GPX4 axis
    Lai, Jian-qin
    Zhao, Le-le
    Hong, Chao
    Zou, Qiu-ming
    Su, Jin-xuan
    Li, Si-jia
    Zhou, Xiao-feng
    Li, Zi-sheng
    Deng, Bo
    Cao, Jie
    Qi, Qi
    ACTA PHARMACOLOGICA SINICA, 2024, 45 (08) : 1715 - 1726
  • [9] Licochalcone A Induces Ferroptosis in Hepatocellular Carcinoma via Reactive Oxygen Species Activated by the SLC7A11/GPX4 Pathway
    Zhang, Jin-Xin
    Xiao, Yan
    Li, Yi-Quan
    Zhu, Yi-Long
    Li, Ya-Ru
    Zhao, Ren-Shuang
    Jin, Ning-Yi
    Fang, Jin-Bo
    Li, Xiao
    Han, Ji-Cheng
    INTEGRATIVE CANCER THERAPIES, 2023, 22
  • [10] Ascorbic acid induces ferroptosis via STAT3/GPX4 signaling in oropharyngeal cancer
    Wu, Kaiyuan
    Liu, Le
    Wu, Zhenhua
    Huang, Qi
    Zhou, Lei
    Xie, Rujiao
    Wang, Miao
    FREE RADICAL RESEARCH, 2024, 58 (02) : 117 - 129
12345