Recent advances in FeCl3-photocatalyzed organic reactions via hydrogen-atom transfer

In recent years, FeCl 3 -photocatalyzed direct C-H/Si-H bond functionalization reactions have attracted huge attention. In those transformations, chlorine radical (Cl center dot ) could be generated from FeCl 3 via a ligandto-metal charge transfer (LMCT)/homolysis process under light irradiation. The resulting chlorine radical subsequently acts as a hydrogen atom transfer (HAT) agent to abstract the hydrogen atom of aliphatic C-H, O-H, or Si-H bonds to give the corresponding C/Si/O-centered radicals for various organic transformations. In this review, we summarized the recent advances in the application of FeCl 3 as a HAT photocatalyst for the C/Si-H functionalization to construct C-C, C-N, C-Si, C-S, C-B, and C -P bonds. (c) 2024 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.