Environmental occurrence, biological effects, and health implications of zinc pyrithione: A review

被引：2

作者：

Wu, Xintong ^{[1
]}

Jeong, Chang-Bum ^{[2
]}

Huang, Wenlong ^{[3
]}

Ip, Jack Chi-Ho ^{[4
]}

Guo, Jiahua ^{[5
]}

Lai, Keng Po ^{[6
]}

Liu, Wenhua ^{[1
]}

Mo, Jiezhang ^{[1
,7
]}

机构：

[1] Shantou Univ, Guangdong Prov Key Lab Marine Disaster Predict & P, Shantou 515063, Peoples R China

[2] Incheon Natl Univ, Dept Marine Sci, Incheon 22012, South Korea

[3] Shantou Univ Med Coll, Dept Forens Med, Shantou 515041, Guangdong, Peoples R China

[4] Lingnan Univ, Sci Unit, Hong Kong, Peoples R China

[5] Northwest Univ, Coll Urban & Environm Sci, Shaanxi Key Lab Earth Surface Syst & Environm Carr, Xian 710127, Peoples R China

[6] Guilin Med Univ, Educ Dept Guangxi Zhuang Autonomous Reg, Key Lab Environm Pollut & Integrat Om, Guilin 541004, Peoples R China

[7] Shantou Univ, Coll Sci, Dept Biol, Shantou 515063, Guangdong, Peoples R China

来源：

MARINE POLLUTION BULLETIN | 2024年 / 203卷

关键词：

Antifoulant; Environmental fate; Oxidative stress; Apoptosis; Long-term effects; Environmental risk assessment; ANTIFOULING BOOSTER BIOCIDES; KCNQ POTASSIUM CHANNELS; ACUTE TOXICITY; COPPER PYRITHIONE; MITOCHONDRIAL DYSFUNCTION; MIXTURE TOXICITY; CANCER CELLS; STRESS; DEGRADATION; ACTIVATION;

D O I：

10.1016/j.marpolbul.2024.116466

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Due to the detrimental effects on aquatic organisms and ecosystem, tributyltin as a antifouling agent have been banned worldwide since 1990s. As a replacement for tributyltin, zinc pyrithione (ZnPT) has emerged as a new environmentally friendly antifouling agent. However, the widespread use of ZnPT unavoidably leads to the occurrence and accumulation in aquatic environments, especially in waters with limited sunlight. Despite empirical evidence demonstrating the ecotoxicity and health risks of ZnPT to different organisms, there has been no attempt to compile and interpret this data. The present review revealed that over the past 50 years, numerous studies have documented the toxicity of ZnPT in various organisms, both in vitro and in vivo. However, long-term effects and underlying mechanisms of ZnPT on biota, particularly at environmentally realistic exposure levels, remain largely unexplored. In-depth studies are thus necessary to generate detailed ecotoxicological information of ZnPT for environmental risk assessment and management.

引用

页数：11