Natural Antioxidants from Acmella oleracea Extract as Dermatocosmetic Actives

被引:0
作者
Maxim, Claudia [1 ]
Blaga, Alexandra Cristina [1 ]
Cimpoesu, Ramona [2 ]
Zinicovscaia, Inga [3 ,4 ]
Peshkova, Alexandra [3 ]
Danu, Maricel [1 ,5 ]
Barna, Ana Simona [1 ]
Suteu, Daniela [1 ]
机构
[1] Gheorghe Asachi Tech Univ Iasi, Fac Chem Engn & Environm Protect Cristofor Simione, 73 Prof Dimitrie Mangeron St, Iasi 700050, Romania
[2] Gheorghe Asachi Tech Univ Iasi, Fac Mat Sci & Engn, Dept Mat Sci, Prof Dr Docent D Mangeron Blvd 41, Iasi 700259, Romania
[3] Joint Inst Nucl Res, 6 Joliot Curie Str, Dubna 141980, Russia
[4] Horia Hulubei Natl Inst R&D Phys & Nucl Engn, 30 Reactorului Str, Magurele 077125, Ilfov, Romania
[5] Petru Poni Inst Macromol Chem, 41A Grigore Ghica Voda Alley, Iasi 700487, Romania
关键词
Acmella oleracea; dermatocosmetic field; emulsions; skin oxidative stress; INGREDIENTS; PENETRATION; EMULSIONS;
D O I
10.3390/scipharm92030052
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Compounds from plant extracts make dermatocosmetic products more effective as they avoid the adaptation and resistance of the organism and achieve a synergistic effect of the molecular properties of interest. Acmella oleracea extract is considered to have great potential in preventing oxidative damage and improving the appearance of the skin. The purpose of this article is to support the product formulated by preliminary studies of two types of O/W emulsions with 3% and 5% concentrations of Acmella oleracea extract. Physico-chemical methods were performed to evaluate the stability, microbiological control, rheological behavior and diffusion through the membrane. Good homogeneity, structural strength and flexibility, adequate skin diffusion, and high physico-chemical and microbiological stability were confirmed. The conclusions lead to the idea that these results require further in vivo studies as well as studies of toxicity and cytotoxicity to obtain the necessary data to place this product on the market.
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页数:13
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