Molecular Imaging of Steroid Receptors in Breast Cancer

被引：1

作者：

Keigley, Quinton J. ^{[1
]}

Fowler, Amy M. ^{[1
,2
,3
]}

O'Brien, Sophia R. ^{[4
]}

Dehdashti, Farrokh ^{[5
]}

机构：

[1] Univ Wisconsin, Sch Med & Publ Hlth, Dept Radiol, Madison, WI USA

[2] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA

[3] Univ Wisconsin, Sch Med & Publ Hlth, Dept Med Phys, Madison, WI USA

[4] Univ Penn, Perelman Sch Med, Dept Radiol, Philadelphia, PA USA

[5] Washington Univ, Edward Mallinckrodt Inst Radiol, Alvin J Siteman Canc Ctr, Div Nucl Med,Sch Med, 510 S Kingshighway Blvd, St. Louis, MO 63110 USA

来源：

CANCER JOURNAL | 2024年 / 30卷 / 03期

关键词：

Estrogen receptor; progesterone receptor; androgen receptor; positron emission tomography; breast cancer; POSITRON-EMISSION-TOMOGRAPHY; LIGAND-BINDING ASSAY; PHASE-II TRIAL; PROGESTERONE-RECEPTOR; ESTROGEN-RECEPTORS; ENDOCRINE THERAPY; HORMONE RECEPTORS; F-18-FES PET; FES-PET; F-18-FLUOROESTRADIOL PET/CT;

D O I：

10.1097/PPO.0000000000000715

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Steroid receptors regulate gene expression for many important physiologic functions and pathologic processes. Receptors for estrogen, progesterone, and androgen have been extensively studied in breast cancer, and their expression provides prognostic information as well as targets for therapy. Noninvasive imaging utilizing positron emission tomography and radiolabeled ligands targeting these receptors can provide valuable insight into predicting treatment efficacy, staging whole-body disease burden, and identifying heterogeneity in receptor expression across different metastatic sites. This review provides an overview of steroid receptor imaging with a focus on breast cancer and radioligands for estrogen, progesterone, and androgen receptors.

引用

页码：142 / 152

页数：11

共 50 条

[41] Review: Receptor Targeted Nuclear Imaging of Breast Cancer [J].

Dalm, Simone U. ;

Verzijlbergen, John Fred ;

De Jong, Marion .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (02)

[42] PET Imaging for Breast Cancer [J].

Fowler, Amy M. ;

Cho, Steve Y. .

RADIOLOGIC CLINICS OF NORTH AMERICA, 2021, 59 (05) :725-735

[43] The correlation between imaging findings and breast cancer cell receptors status [J].

Fatehi, Pegah ;

Mahboubi-Fooladi, Zahra ;

Dastmardi, Maedeh ;

Esfehani, Reza Jafarzadeh ;

Bagheri, Arash Khameneh .

JOURNAL OF MEDICAL IMAGING AND RADIATION SCIENCES, 2023, 54 (03) :446-450

[44] Genome-wide crosstalk between steroid receptors in breast and prostate cancers [J].

Paakinaho, Ville ;

Palvimo, Jorma J. .

[45] Heterogeneity in hormone-dependent breast cancer and therapy: Steroid hormones, HER2, melanoma antigens, and cannabinoid receptors [J].

Kunstic, Tajda Tavcar ;

Debeljak, Natasa ;

Tacer, Klementina Fon .

ADVANCES IN CANCER BIOLOGY-METASTASIS, 2023, 7

[46] Epithelial-Mesenchymal Transition (EMT) and Regulation of EMT Factors by Steroid Nuclear Receptors in Breast Cancer: A Review and in Silico Investigation [J].

Voutsadakis, Ioannis A. .

JOURNAL OF CLINICAL MEDICINE, 2016, 5 (01)

[47] Molecular imaging as biomarker for treatment response and outcome in breast cancer [J].

van Geel, Jasper J. L. ;

de Vries, Erik F. J. ;

van Kruchten, Michel ;

Hospers, Geke A. P. ;

Glaudemans, Andor W. J. M. ;

Schroder, Carolina P. .

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2023, 15

[48] Progesterone receptors - animal models and cell signaling in breast cancer: Role of steroid receptor coactivators and corepressors of progesterone receptors in breast cancer [J].

Xiuhua Gao ;

Zafar Nawaz .

Breast Cancer Research, 4

[49] Progesterone receptors - animal models and cell signaling in breast cancer - Role of steroid receptor coactivators and corepressors of progesterone receptors in breast cancer [J].

Gao, XH ;

Nawaz, Z .

BREAST CANCER RESEARCH, 2002, 4 (05) :182-186

[50] PET imaging of oestrogen receptors in patients with breast cancer [J].

van Kruchten, Michel ;

de Vries, Elisabeth G. E. ;

Brown, Myles ;

de Vries, Erik F. J. ;

Glaudemans, Andor W. J. M. ;

Dierckx, Rudi A. J. O. ;

Schroder, Carolien P. ;

Hospers, Geke A. P. .

LANCET ONCOLOGY, 2013, 14 (11) :E465-E475

← 1 2 3 4 5 →