Evaluating Thromboprophylaxis Strategies for High-Risk Pregnancy: A Current Perspective

被引：4
|
作者：
Stanciakova, Lucia [1 ]
Brisudova, Kristina [2 ]
Skornova, Ingrid [1 ]
Bolek, Tomas [2 ]
Samos, Matej [2 ]
Biringer, Kamil [3 ]
Stasko, Jan [1 ]
Sokol, Juraj [1 ]
机构：
[1] Comenius Univ, Jessenius Fac Med Martin, Natl Ctr Hemostasis & Thrombosis, Dept Hematol & Transfus Med,Martin Univ Hosp, Martin 03601, Slovakia
[2] Comenius Univ, Martin Univ Hosp, Jessenius Fac Med Martin, Dept Internal Med 1, Martin 03601, Slovakia
[3] Comenius Univ, Martin Univ Hosp, Jessenius Fac Med Martin, Dept Gynecol & Obstet, Martin 03601, Slovakia
来源：
PHARMACEUTICALS | 2024年 / 17卷 / 06期
关键词：
risk factors; at-risk pregnant patients; venous thromboembolism; thromboprophylaxis; OVARIAN HYPERSTIMULATION SYNDROME; RECURRENT VENOUS THROMBOEMBOLISM; PHYSIOLOGICAL-CHANGES; THROMBOSIS; PREVENTION; MANAGEMENT; WOMEN; PUERPERIUM; SOCIETY; PATHOPHYSIOLOGY;
D O I：
10.3390/ph17060773
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Venous thromboembolism (VTE) represents one of the leading causes of death during pregnancy. The greatest risk for it is the presence of medical or family history of VTE, stillbirth, cesarean section and selected thrombophilia. Appropriate thromboprophylaxis has the potential to decrease the risk of VTE in at-risk pregnant patients by 60-70%. Based on this, the authors reviewed the PubMed, Web of Science and Scopus databases to identify the possibilities of thromboprophylaxis in pregnant patients with a high risk of VTE. Moreover, they summarized its management in specific situations, such as cesarean delivery or neuraxial blockade. Currently, low-molecular-weight heparins (LMWH) are the preferred drugs for anticoagulant thromboprophylaxis in the course of pregnancy and postpartum due to easy administration and a lower rate of adverse events.
引用
收藏
页数：34
相关论文
共 50 条
  • [1] Advances in Thromboprophylaxis for High-Risk Pregnancies: A Comprehensive Review of Current Strategies and Emerging Approaches
    Dahiphale, Swati M.
    Dewani, Deepika
    Dahiphale, Jayashree M.
    Agrawal, Manjusha
    Dave, Apoorva
    Pajai, Sandhya
    Jyotsna, Garapati
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (08)
  • [2] Thromboprophylaxis during Pregnancy and the Puerperium: Highlights from Current Guidelines
    Rath, W.
    ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, 2010, 214 (06): : 217 - 228
  • [3] Thromboprophylaxis with fondaparinux in high-risk postoperative patients with renal insufficiency
    Hester, Willie
    Fry, Caitlyn
    Gonzalez, Daniel
    Cohen-Wolkowiez, Michael
    Inman, Brant A.
    Ortel, Thomas L.
    THROMBOSIS RESEARCH, 2014, 133 (04) : 629 - 633
  • [4] Prescription of extended-duration thromboprophylaxis after high-risk, abdominopelvic cancer surgery
    Wright, Jason D.
    Chen, Ling
    Jorge, Soledad
    Burke, William M.
    Tergas, Ana I.
    Hou, June Y.
    Hu, Jim C.
    Neugut, Alfred I.
    Ananth, Cande V.
    Hershman, Dawn L.
    GYNECOLOGIC ONCOLOGY, 2016, 141 (03) : 531 - 537
  • [5] How can Secondary Thromboprophylaxis in High-Risk Pregnant Patients be Improved?
    Stanciakova, Lucia
    Dobrotova, Miroslava
    Holly, Pavol
    Zolkova, Jana
    Vadelova, Lubica
    Skornova, Ingrid
    Ivankova, Jela
    Samos, Matej
    Bolek, Tomas
    Grendar, Marian
    Danko, Jan
    Kubisz, Peter
    Stasko, Jan
    CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2022, 28
  • [6] Pharmacological Thromboprophylaxis during Pregnancy and the Puerperium: Recommendations from Current Guidelines and their Critical Comparison
    Rath, W.
    Tsikouras, P.
    von Tempelhoff, G. -F.
    ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, 2016, 220 (03): : 95 - 105
  • [7] Pregnancy-related venous thromboembolism: Risk and the effect of thromboprophylaxis
    Lussana, Federico
    Coppens, Michiel
    Cattaneo, Marco
    Middeldorp, Saskia
    THROMBOSIS RESEARCH, 2012, 129 (06) : 673 - 680
  • [8] How can Secondary Thromboprophylaxis in High-Risk Pregnant Patients be Improved?
    Stanciakova, Lucia
    Dobrotova, Miroslava
    Holly, Pavol
    Zolkova, Jana
    Vadelova, Lubica
    Skornova, Ingrid
    Ivankova, Jela
    Samos, Matej
    Bolek, Tomas
    Grendar, Marian
    Danko, Jan
    Kubisz, Peter
    Stasko, Jan
    CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2022, 28
  • [9] Sodium pentosan polysulfate efficacy as thromboprophylaxis agent in high-risk women following gynecological surgery
    Indirayani, Ima
    Kalok, Aida
    Ismail, Nik A. Nik
    Shah, Shamsul A.
    Lim, Pei S.
    Ismail, Nor A. Mohamed
    Azurah, Abdul G. Nur
    Omar, Mohd Hashim
    Shafiee, Mohamad N.
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2018, 44 (08) : 1458 - 1465
  • [10] High-Risk Pregnancy
    Holness, Nola
    NURSING CLINICS OF NORTH AMERICA, 2018, 53 (02) : 241 - +
12345