Application of nanoscale metal-organic frameworks in tumor immunotherapy

被引：3
作者：
Zeng, Xiao-Xuan [1 ,2 ]
Lu, Jing-Sheng [1 ,2 ]
Ma, Dong-Wei [1 ,2 ]
Huang, Yu-Ting [1 ,2 ]
Chen, Ling [1 ,2 ]
Wang, Gang [1 ,2 ]
Chen, Qing [1 ,2 ]
Lin, Ning [1 ,2 ]
机构：
[1] Guangxi Univ Chinese Med, Coll Pharm, Guangxi Sci Res Ctr Tradit Chinese Med, Nanning 530200, Peoples R China
[2] Guangxi Zhuang Yao Med Ctr Engn & Technol, Nanning 530200, Peoples R China
来源：
RARE METALS | 2024年 / 43卷 / 10期
基金：
芬兰科学院; 中国国家自然科学基金;
关键词：
Metal-organic frameworks; Tumor; Immunotherapy; Drug delivery system; DRUG-DELIVERY; COLD TUMORS; NANOPARTICLES; THERAPY; RELEASE; ANTIGEN; CELLS; HOT;
D O I：
10.1007/s12598-024-02779-6
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Immunotherapy has attracted wide attention because it can not only kill tumor cells but also effectively prevent tumor recurrence. However, due to the poor efficacy of the monotherapy in tumor immunotherapy, combination therapies are needed to enhance their efficacy, such as chemodynamic therapy/immunotherapy, photodynamic therapy/immunotherapy, sonodynamic therapy/immunotherapy and so on. Nanoscale metal-organic frameworks (nMOFs) are widely used for drug delivery because of their rich and variable composition, high drug loading capacity and good biodegradability. Compared with other conventional drug delivery systems (DDSs), nMOFs play more advantageous role in inducing immune cell death of tumor cells and combination therapies. This article focuses on the application of nMOFs in tumor immunotherapy in terms of their use as gatekeepers, supplementary agents and drug carriers, respectively, with the aim of providing some ideas and references for the design of smart nanoscale DDS for tumor immunotherapy.
引用
收藏
页码：4867 / 4883
页数：17
相关论文
共 128 条
[1]   Sustained and targeted delivery of checkpoint inhibitors by metal-organic frameworks for cancer immunotherapy [J].
Alsaiari, Shahad K. ;
Qutub, Somayah S. ;
Sun, Shichao ;
Baslyman, Walaa ;
Aldehaiman, Mansour ;
Alyami, Mram ;
Almalik, Abdulaziz ;
Halwani, Rabih ;
Merzaban, Jasmeen ;
Mao, Zhengwei ;
Khashab, Niveen M. .
SCIENCE ADVANCES, 2021, 7 (04)
[2]   Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67 [J].
Alshammari, Abdulraman M. ;
Smith, D. David ;
Parriott, Jake ;
Stewart, Jason P. ;
Curran, Stephen M. ;
McCulloh, Russell J. ;
Barry, Peter A. ;
Iyer, Smita S. ;
Palermo, Nicholas ;
Phillips, Joy A. ;
Dong, Yuxiang ;
Ronning, Donald R. ;
Vennerstrom, Jonathan L. ;
Sanderson, Sam D. ;
Vetro, Joseph A. .
ACS INFECTIOUS DISEASES, 2020, 6 (05) :1169-1181
[3]   Cancer stem cells revisited [J].
Batlle, Eduard ;
Clevers, Hans .
NATURE MEDICINE, 2017, 23 (10) :1124-1134
[4]   Terminology of metal-organic frameworks and coordination polymers (IUPAC Recommendations 2013) [J].
Batten, Stuart R. ;
Champness, Neil R. ;
Chen, Xiao-Ming ;
Garcia-Martinez, Javier ;
Kitagawa, Susumu ;
Ohrstrom, Lars ;
O'Keeffe, Michael ;
Suh, Myunghyun Paik ;
Reedijk, Jan .
PURE AND APPLIED CHEMISTRY, 2013, 85 (08) :1715-1724
[5]   Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms [J].
Billesbolle, Christian B. ;
Azumaya, Caleigh M. ;
Kretsch, Rachael C. ;
Powers, Alexander S. ;
Gonen, Shane ;
Schneider, Simon ;
Arvedson, Tara ;
Dror, Ron O. ;
Cheng, Yifan ;
Manglik, Aashish .
NATURE, 2020, 586 (7831) :807-+
[6]   Metal Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery [J].
Cai, Wen ;
Wang, Junqing ;
Chu, Chengchao ;
Chen, Wei ;
Wu, Chunsheng ;
Liu, Gang .
ADVANCED SCIENCE, 2019, 6 (01)
[7]   Chitosan coated biocompatible zeolitic imidazolate framework ZIF-90 for targeted delivery of anticancer drug methotrexate [J].
Cao, Xiang-Xin ;
Liu, Shui-Li ;
Lu, Jing-Sheng ;
Zhang, Zhen-Wei ;
Wang, Gang ;
Chen, Qing ;
Lin, Ning .
JOURNAL OF SOLID STATE CHEMISTRY, 2021, 300
[8]   In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment [J].
Chen, Qian ;
Wang, Chao ;
Zhang, Xudong ;
Chen, Guojun ;
Hu, Quanyin ;
Li, Hongjun ;
Wang, Jinqiang ;
Wen, Di ;
Zhang, Yuqi ;
Lu, Yifei ;
Yang, Guang ;
Jiang, Chen ;
Wang, Jun ;
Dotti, Gianpietro ;
Gu, Zhen .
NATURE NANOTECHNOLOGY, 2019, 14 (01) :89-+
[9]   Delivery Strategies for Immune Checkpoint Blockade [J].
Chen, Qian ;
Wang, Chao ;
Chen, Guojun ;
Hu, Quanyin ;
Gu, Zhen .
ADVANCED HEALTHCARE MATERIALS, 2018, 7 (20)
[10]   2D Copper(II) Metalated Metal-Organic Framework Nanocomplexes for Dual-enhanced Photodynamic Therapy and Amplified Antitumor Immunity [J].
Chen, Zixuan ;
Wu, Yafeng ;
Yao, Zhipeng ;
Su, Juan ;
Wang, Zhi ;
Xia, Hongping ;
Liu, Songqin .
ACS APPLIED MATERIALS & INTERFACES, 2022, 14 (39) :44199-44210
12345678910