An unusual cause of significantly elevated blood alpha-fetoprotein levels: a case report and literature review

被引：0
|
作者：
Zheng, Yue [1 ]
Yao, Jianping [2 ]
Liu, Jin [3 ]
Zhao, Feimin [1 ]
机构：
[1] Zhejiang Chinese Med Univ, Affiliated Cent Hosp Huzhou Univ, Huzhou Cent Hosp, Dept Gen Med,Sch Clin Med 5, Huzhou, Zhejiang, Peoples R China
[2] Zhejiang Chinese Med Univ, Affiliated Cent Hosp Huzhou Univ, Huzhou Cent Hosp, Dept Endocrinol,Sch Clin Med 5, Huzhou, Zhejiang, Peoples R China
[3] Zhejiang Chinese Med Univ, Affiliated Cent Hosp Huzhou Univ, Huzhou Cent Hosp, Dept Pathol,Sch Clin Med 5, Huzhou, Zhejiang, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2024年 / 14卷
关键词：
alpha-fetoprotein; gastric cancer; gastric hepatoid adenocarcinoma; metastasis; clinical application; GASTRIC-CANCER; HEPATOID ADENOCARCINOMA; AFP; PROGNOSIS; STOMACH;
D O I：
10.3389/fonc.2024.1393074
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Alpha-fetoprotein (AFP) serves as a crucial diagnostic marker for primary hepatocellular carcinoma (HCC) and germ cell tumors (GCTs), with rare instances of significantly elevated levels in other diseases. In this study, we present a case of an elderly patient who was diagnosed with AFP-producing gastric cancer (AFPGC) following an elevated AFP result during physical examination. In investigating liver cancer at an early stage, the diagnosis was missed because of failure in detecting the lesion, resulting in delayed treatment initiation. AFPGC is a rare aggressive tumor that demands heightened awareness among clinicians to foster early detection, diagnosis, and treatment for improved prognosis.
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页数：5
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