Treatment Approaches to Myasthenia Gravis and Obstructive Sleep Apnea: Case Report

被引：0

作者：

Iafigliola, Sergio Giamas ^{[1
]}

Guimaraes, Thais Moura ^{[2
]}

D'Almeida, Vania ^{[1
,2
]}

Poyares, Dalva ^{[2
]}

Dal-Fabbro, Cibele ^{[3
,4
]}

Tufik, Sergio ^{[2
]}

Moreira, Gustavo A. ^{[1
,2
]}

机构：

[1] Univ Fed Sao Paulo Unifesp, Dept Cirurgia, Escola Paulista Med, Sao Paulo, SP, Brazil

[2] Univ Fed Sao Paulo Unifesp, Dept Psicobiol, Escola Paulista Med, Sao Paulo, SP, Brazil

[3] Univ Montreal, Res Ctr Le Ctr Integre Univ St, Serv Sociaux CIUSSS Nord Delile Demontreal, Montreal, PQ, Canada

[4] Univ Montreal, Fac Dent, Montreal, PQ, Canada

来源：

SLEEP SCIENCE | 2024年 / 17卷 / 04期

关键词：

mandibular advancement device; myasthenia gravis; obstructive sleep apnea; MUSCLE; DISORDERS;

D O I：

10.1055/s-0044-1780502

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Myasthenia gravis (MG) is a chronic autoimmune disease characterized by progressive weakness and skeletal muscle fatigue due to the destruction of acetylcholine receptors, causing an abnormality in the synaptic junction between innervation and muscle fibers. The treatment of patients with MG and obstructive sleep apnea (OSA) is positive pressure in the airway; however, the lack of adherence to the protocol can lead to increased morbidity. A known alternative treatment for OSA is the mandibular advancement device (MAD). The objective of the present report is to describe an emblematic case of a 50-year-old male patient with MG with sleep complaints and documented OSA, and his response to different treatment approaches.

引用

页码：e466 / e469

页数：4

共 19 条

[1] Current Treatment of Myasthenia Gravis [J].

Alhaidar, Mohammed K. ;

Abumurad, Sumayyah ;

Soliven, Betty ;

Rezania, Kourosh .

JOURNAL OF CLINICAL MEDICINE, 2022, 11 (06)

[2] Diagnostic and clinical classification of autoimmune myasthenia gravis [J].

Berrih-Aknin, Sonia ;

Frenkian-Cuvelier, Melinee ;

Eymard, Bruno .

JOURNAL OF AUTOIMMUNITY, 2014, 48-49 :143-148

[3] Sleep Disorders in Neuromuscular Diseases [J].

Bhat, Sushanth ;

Gupta, Divya ;

Chokroverty, Sudhansu .

NEUROLOGIC CLINICS, 2012, 30 (04) :1359-+

[4]

Diaz-Abad Montserrat, 2019, Innov Clin Neurosci, V16, P11

[5] Maxillary deformity following CPAP treatment in myasthenia gravis [J].

Haviv, Yaron ;

Leibovitz, Shirley ;

Almoznino, Galit ;

Sharav, Yair ;

Zilberman, Uri .

CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE, 2018, 36 (06) :404-407

[6] CPAP Therapy Reverses Weakness of Myasthenia Gravis: Role of Obstructive Sleep Apnea in Paradoxical Weakness of Myasthenia Gravis [J].

Ji, Ki-Hwan ;

Bae, Jong Seok .

JOURNAL OF CLINICAL SLEEP MEDICINE, 2014, 10 (04) :441-442

[7] Sleep Disordered Breathing Mimicking Myasthenia Crisis in a Patient with Myasthenia Gravis [J].

Lai, Yi-Chun ;

Chen, Jung-Yueh ;

Wu, Huey-Dong ;

Yang, Chih-Chao ;

Lin, Chin-Hsien ;

Lee, Pei-Lin .

JOURNAL OF CLINICAL SLEEP MEDICINE, 2016, 12 (05) :767-769

[8] The use of oral appliances in obstructive sleep apnea: a retrospective cohort study spanning 14 years of private practice experience [J].

Mintz, Sylvan S. ;

Kovacs, Reka .

SLEEP AND BREATHING, 2018, 22 (02) :541-546

[9] Relationship between Muscle Fiber Conduction Velocity and the Force-time Curve during Muscle Twitches [J].

Murakami, Kenichi ;

Fujisawa, Hiroyuki ;

Onobe, Jun ;

Sato, Yoichiro .

JOURNAL OF PHYSICAL THERAPY SCIENCE, 2014, 26 (04) :621-624

[10] Sleep apnea in patients with myasthenia gravis [J].

Nicolle, M. W. ;

Rask, S. ;

Koopman, W. J. ;

George, C. F. P. ;

Adams, J. ;

Wiebe, S. .

NEUROLOGY, 2006, 67 (01) :140-142

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