Use and Intensi fi cation of Oral Guideline-Directed Medical Therapy in Hospitalized Patients With Heart Failure and Reduced Ejection Fraction

Adults with heart failure with reduced ejection fraction are at increased risk for morbidity and mortality, especially if hospitalized for acute decompensation. Evidence -based medication therapies are frequently underused or inappropriately prescribed, which further exacerbates poor outcomes for these patients. Provider inertia has been identi fied as a leading cause of poor medication utilization. Nurse practitioners in an acute care setting are uniquely positioned to improve outcomes by prescribing and intensifying oral therapies during acute decompensated heart failure. This article describes the current evidence -related core guidelinedirected medical therapy along with strategies for intensi fication during hospitalization. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.