Menopause, epicardial adiposity and preserved ejection fraction heart failure

被引：0
作者：
Museedi, Abdulrahman S. [1 ]
Samson, Rohan [2 ]
Le Jemtel, Thierry H. [1 ]
机构：
[1] Tulane Univ, Sch Med, John W Deming Dept Med, Sect Cardiol, 1430 Tulane Ave,Box 8548, New Orleans, LA 70112 USA
[2] Univ Louisville Hlth, Jewish Hosp, Adv Heart Failure Therapies Program, 201 Abraham Flexner Way, Suite 1001, Louisville, KY 40202 USA
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2024年 / 415卷
关键词：
Epicardial fat; Visceral fat; HFpEF; Obesity; LEFT-VENTRICULAR STRUCTURE; VISCERAL FAT; BARIATRIC SURGERY; CARDIOVASCULAR FAT; MIDLIFE WOMEN; TISSUE; OBESITY; ATHEROSCLEROSIS; INFLAMMATION; DECREASE;
D O I：
10.1016/j.ijcard.2024.132478
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Postmenopausal women are overrepresented in the preserved ejection heart failure population. Expansion of visceral and epicardial adipose tissue during the menopause transition leads to local and low-grade systemic inflammation that in turn contributes to left ventricular concentric remodeling, diastolic dysfunction and the development and progression of preserved ejection fraction. In contrast to visceral adipose tissue imaging, epicardial adipose tissue can be inexpensively imaged on low radiation coronary calcium score computerized tomography examination. The menopause transition provides a unique time frame to evaluate the contribution of epicardial adipose tissue expansion to the pathogenesis of preserved ejection heart failure.
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页数：5
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