Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities

被引：0

作者：

Puyo, Pablo Velasco ^{[1
]}

Tagarro, Alfredo ^{[2
,3
,4
]}

Garcia-Obregon, Susana ^{[5
,6
]}

Bejarano, Olatz Villate ^{[5
]}

Moraleda, Cinta ^{[2
,7
]}

Aragones, Jorge Huerta ^{[8
,9
,10
]}

Cancho, Eduardo J. Bardon ^{[8
,9
,10
]}

Morros, Anna Faura ^{[11
]}

Galan-Gomez, Victor ^{[12
]}

Fernandez, Laura Escobar ^{[13
]}

Lendinez-Molinos, Francisco ^{[14
]}

Velasco, Blanca Herrero ^{[15
]}

Horno, Laura Urena ^{[16
]}

Dominguez-Pinilla, Nerea ^{[17
,18
]}

Gazquez, Juan Francisco Pascual ^{[19
]}

Lozano, Cristina Nova ^{[20
]}

Osuna-Marco, Marta ^{[21
]}

Marin-Cruz, Ines ^{[22
,23
]}

Pastrana, Irene Gomez

Barandiaran, Nagore Garcia de Andoin ^{[24
,25
,26
]}

Mingo, Nerea Gallego ^{[27
]}

Rodriguez, Raquel Portugal ^{[28
]}

Canete, Adela ^{[29
]}

Leon, Marta Pareja ^{[30
]}

Bustamante, Sara Castrillo ^{[31
]}

Garcia, Maria Tallon ^{[32
]}

Gonzalez-Prieto, Almudena ^{[33
]}

Sole-Rodriguez, Maria ^{[34
]}

Cruz, Macarena Gonzalez ^{[35
]}

Soriano-Arandes, Antonio ^{[36
]}

Mota, Miriam ^{[37
]}

Perez-Hoyos, Santiago

Moreno, Lucas ^{[1
]}

Astigarraga, Itziar ^{[38
,39
]}

机构：

[1] Vall dHebron Barcelona Hosp, Pediat Oncol & Hematol Dept, Barcelona, Spain

[2] Inst Invest 12 Octubre, Fdn Invest Biomed Hosp 12 Octubre, imas12, Madrid, Spain

[3] FIIB HUIS HHEN, Dept Pediat, Madrid, Spain

[4] Univ Europea Madrid, Madrid, Spain

[5] BioBizkaia Hlth Res Inst, Pediat Oncol Grp, Baracaldo, Spain

[6] Univ Basque Country, Dept Physiol, Leioa, Spain

[7] Hosp Univ 12 Octubre, Pediat Infect DiseaseUnit, Madrid, Spain

[8] Hosp Materno Infantil Complejo Hosp Gen Univ, Paediat & Adolescent Haematol & Oncol Sect, Paediat Dept, Madrid, Spain

[9] Univ Complutense Madrid, Fac Med, Madrid, Spain

[10] IiSGM, Madrid, Spain

[11] Hosp San Juan Dios, Pediat Oncol & Hematol Unit, Barcelona, Spain

[12] Hosp Infantil Univ La Paz, Pediat Oncol & Hematol Dept, Madrid, Spain

[13] Hosp Clin Univ Valladolid, Pediat Oncol & Hematol Dept, Valladolid, Spain

[14] Hosp Infantil Infanta Leonor, Pediat Oncol & Hematol Dept, Almeria, Spain

[15] Hosp Infantil Univ Nino Jesus, Pediat Oncol & Hematol Unit, Madrid, Spain

[16] Hosp Doctor Balmis Alicante, Alicante, Spain

[17] Complejo Hosp Toledo, Pediat Oncol Unit, Toledo, Spain

[18] Res Inst, Hosp 12 Octubre, Madrid, Spain

[19] Hosp Univ Virgen de Ias Nieves, Pediat Oncol & Hematol Dept, Granada, Spain

[20] Hosp Clin Univ Valencia, Valencia, Spain

[21] HM Hosp, Pediat Oncol & Hematol Unit, Madrid, Spain

[22] Hosp Univ Virgen del Rocio, Dept Rheumatol & Immunol, Paediat Infect Dis, Seville, Spain

[23] Inst Biomed Sevilla, Infect Dis & Immune Syst Area, Congenital Alterat Immun Grp, Seville, Spain

[24] Donostia Univ Hosp, Pediat Oncol & Hematol Unit, San Sebastian, Spain

[25] Biogipuzkoa Hlth Res Inst, Pediat Grp, Paseo Dr Begiristain, San Sebastian, Spain

[26] Univ Basque Country, Pediat Dept, PaseoDr J Beguiristain, San Sebastian, Spain

[27] Hosp Univ Son Espases, Dept Paediat, Mallorca, Spain

[28] Hosp Univ Burgos, Pediat Oncol & Hematol Dept, Burgos, Spain

[29] Hosp Univ Politecn La Fe, Pediat Oncol & Hematol Dept, Valencia, Spain

[30] Hosp Gen Albacete, Dept Paediat, Albacete, Spain

[31] Complejo Asistencial Segovia, Dept Paediat, Segovia, Spain

[32] Hosp Alvaro Cunqueiro, Vigo, Spain

[33] Hosp Univ Salamanca, Pediat Oncol & Hematol Dept, Salamanca, Spain

[34] Hosp Univ Juan Ramon Jimenez, Huelva, Spain

[35] Hosp Univ Canarias, Dept Paediat, Tenerife, Spain

[36] Univ Autonoma Barcelona, Vall dHebron Inst Recerca, Hosp Vall dHebron, Pediat Infect Dis & Immunodeficiencies Unit, Barcelona, Spain

[37] Vall dHebron Res Inst VHIR, Unit Stat & Bioinformat UEB, Barcelona, Spain

[38] Hosp Univ Cruces, Dept Pediat, Baracaldo, Spain

[39] Univ Basque Country, Dept Pediat, Baracaldo, Spain

来源：

PEDIATRIC BLOOD & CANCER | 2024年 / 71卷 / 08期

关键词：

allogenic HSCT; cancer; children; comorbidities; COVID-19; Registry;

D O I：

10.1002/pbc.31120

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The EPICO (Spanish general registry of COVID-19 in children)-SEHOP (Spanish Society of Pediatric Hematology and Oncology) platform gathers data from children with SARS-CoV-2 in Spain, allowing comparison between children with cancer or allogeneic hematopoietic stem cell transplantation (alloHSCT) and those without. The infection is milder in the cancer/alloHSCT group than in children without comorbidities (7.1% vs. 14.7%), except in children with recent alloHSCT (less than 300 days), of which 35.7% experienced severe COVID-19. These data have been shared with the SEHOP members to support treatment and isolation policies akin to those for children without cancer, except for those with recent alloHSCT or additional comorbidities. This highlights the collaborative registries potential in managing pandemic emergencies.

引用

页数：7

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