Five-Year Follow-Up of Choroidal Metastasis From Lung Adenocarcinoma Harboring Epidermal Growth Factor Receptor (EGFR) Mutation: A Case Report and Literature Review

被引：0
|
作者：
Nakashima, Koki [1 ]
Demura, Yoshiki [2 ]
Tada, Toshihiko [2 ]
Ishizuka, Tamotsu [1 ]
机构：
[1] Univ Fukui, Dept Resp Med, Fukui, Japan
[2] Japanese Red Cross Fukui Hosp, Dept Resp Med, Fukui, Japan
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 08期
关键词：
bevacizumab; pemetrexed; egfr-tki; epidermal growth factor receptor (egfr); ocular metastasis; choroidal metastasis; lung cancer; CANCER; OSIMERTINIB; THERAPY; VISION;
D O I：
10.7759/cureus.66537
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This is a long-term follow-up case report of a 71-year-old man with lung adenocarcinoma and choroidal metastasis harboring an epidermal growth factor receptor mutation. Blurry vision, caused by the choroidal metastasis, improved with first-line treatment with afatinib. Thereafter, osimertinib was administered as a second-line treatment, then chemotherapy containing pemetrexed plus bevacizumab as a third-line treatment. For 61 months, recurrence of choroidal metastasis was absent. Only a few reports of lung cancer with choroidal metastasis provide long-term follow-up of more than five years. Therefore, the clinical course of this patient may provide some insights for long-term management in such cases.
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页数：6
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