Exploring Pathogen Presence Prediction in Pastured Poultry Farms through Transformer-Based Models and Attention Mechanism Explainability

被引:0
作者
Das, Athish Ram [1 ]
Pillai, Nisha [2 ]
Nanduri, Bindu [1 ]
Rothrock Jr, Michael J. [3 ]
Ramkumar, Mahalingam [2 ]
机构
[1] Mississippi State Univ, Coll Vet Med, Dept Comparat Biomed Sci, Starkville, MS 39762 USA
[2] Mississippi State Univ, Dept Comp Sci & Engn, Starkville, MS 39762 USA
[3] USDA ARS, US Natl Poultry Res Ctr, Egg Safety & Qual Res Unit, Athens, GA 30605 USA
关键词
food safety; pathogen; transformer; PageRank; ANTIBIOTIC-RESISTANCE; SEQUENCES; DIVERSITY; FOOD;
D O I
10.3390/microorganisms12071274
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this study, we explore how transformer models, which are known for their attention mechanisms, can improve pathogen prediction in pastured poultry farming. By combining farm management practices with microbiome data, our model outperforms traditional prediction methods in terms of the F1 score-an evaluation metric for model performance-thus fulfilling an essential need in predictive microbiology. Additionally, the emphasis is on making our model's predictions explainable. We introduce a novel approach for identifying feature importance using the model's attention matrix and the PageRank algorithm, offering insights that enhance our comprehension of established techniques such as DeepLIFT. Our results showcase the efficacy of transformer models in pathogen prediction for food safety and mark a noteworthy contribution to the progress of explainable AI within the biomedical sciences. This study sheds light on the impact of effective farm management practices and highlights the importance of technological advancements in ensuring food safety.
引用
收藏
页数:18
相关论文
共 65 条
  • [1] Peeking Inside the Black-Box: A Survey on Explainable Artificial Intelligence (XAI)
    Adadi, Amina
    Berrada, Mohammed
    [J]. IEEE ACCESS, 2018, 6 : 52138 - 52160
  • [2] Bacteriocin-Producing Probiotic Lactic Acid Bacteria in Controlling Dysbiosis of the Gut Microbiota
    Anjana
    Tiwari, Santosh Kumar
    [J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12
  • [3] Poultry gut health - microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies
    Aruwa, Christiana Eleojo
    Pillay, Charlene
    Nyaga, Martin M.
    Sabiu, Saheed
    [J]. JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 2021, 12 (01)
  • [4] Machine learning for microbiologists
    Asnicar, Francesco
    Thomas, Andrew Maltez
    Passerini, Andrea
    Waldron, Levi
    Segata, Nicola
    [J]. NATURE REVIEWS MICROBIOLOGY, 2024, 22 (04) : 191 - 205
  • [5] Authority European Food Safety, 2018, EFSa J, V16
  • [6] Important ecophysiological roles of non-dominant Actinobacteria in plant residue decomposition, especially in less fertile soils
    Bao, Yuanyuan
    Dolfing, Jan
    Guo, Zhiying
    Chen, Ruirui
    Wu, Meng
    Li, Zhongpei
    Lin, Xiangui
    Feng, Youzhi
    [J]. MICROBIOME, 2021, 9 (01)
  • [7] Changes in the Microbial Community in Soybean Plots Treated with Biochar and Poultry Litter
    Calderon, Rosalie B.
    Jeong, Changyoon
    Ku, Hyun-Hwoi
    Coghill, Lyndon M.
    Ju, Young Jeong
    Kim, Nayong
    Ham, Jong Hyun
    [J]. AGRONOMY-BASEL, 2021, 11 (07):
  • [8] Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
    Caporaso, J. Gregory
    Lauber, Christian L.
    Walters, William A.
    Berg-Lyons, Donna
    Lozupone, Catherine A.
    Turnbaugh, Peter J.
    Fierer, Noah
    Knight, Rob
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 : 4516 - 4522
  • [9] QIIME allows analysis of high-throughput community sequencing data
    Caporaso, J. Gregory
    Kuczynski, Justin
    Stombaugh, Jesse
    Bittinger, Kyle
    Bushman, Frederic D.
    Costello, Elizabeth K.
    Fierer, Noah
    Pena, Antonio Gonzalez
    Goodrich, Julia K.
    Gordon, Jeffrey I.
    Huttley, Gavin A.
    Kelley, Scott T.
    Knights, Dan
    Koenig, Jeremy E.
    Ley, Ruth E.
    Lozupone, Catherine A.
    McDonald, Daniel
    Muegge, Brian D.
    Pirrung, Meg
    Reeder, Jens
    Sevinsky, Joel R.
    Tumbaugh, Peter J.
    Walters, William A.
    Widmann, Jeremy
    Yatsunenko, Tanya
    Zaneveld, Jesse
    Knight, Rob
    [J]. NATURE METHODS, 2010, 7 (05) : 335 - 336
  • [10] PyNAST: a flexible tool for aligning sequences to a template alignment
    Caporaso, J. Gregory
    Bittinger, Kyle
    Bushman, Frederic D.
    DeSantis, Todd Z.
    Andersen, Gary L.
    Knight, Rob
    [J]. BIOINFORMATICS, 2010, 26 (02) : 266 - 267