Evaluation of choroid vascular layer thickness in wet age-related macular degeneration using artificial intelligence

被引：2

作者：

Song, Dan ^{[1
]}

Ni, Yuan ^{[2
]}

Zhou, Ying ^{[1
]}

Niu, Yaqian ^{[1
]}

Wang, Guanzheng ^{[2
]}

Lv, Bin ^{[2
]}

Xie, Guotong ^{[2
,3
]}

Liu, Guangfeng ^{[1
]}

机构：

[1] Peking Univ, Int Hosp, Dept Ophthalmol, 1 Shengmingyuan Rd,Zhongguancun Life Sci Pk, Beijing, Peoples R China

[2] PingAn IFC, Ping An Technol, 12F Bldg B,1-3 Xinyuan South Rd, Beijing 100027, Peoples R China

[3] Ping An Hlth Cloud Co Ltd, PingAn IFC, 12F Bldg B,1-3 Xinyuan South Rd, Beijing 100027, Peoples R China

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2024年 / 47卷

关键词：

Wet age -related macular degeneration; Artificial intelligence; Choroidal thickness; Haller layer thickness; Sattler layer-choriocapillaris complex thickness; OCT; PROGRESSION;

D O I：

10.1016/j.pdpdt.2024.104218

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: To facilitate the assessment of choroid vascular layer thickness in patients with wet age-related macular degeneration (AMD) using artificial intelligence (AI). Methods: We included 194 patients with wet AMD and 225 healthy participants. Choroid images were obtained using swept-source optical coherence tomography. The average Sattler layer-choriocapillaris complex thickness (SLCCT), Haller layer thickness (HLT), and choroidal thickness (CT) were auto-measured at 7 regions centered around the foveola using AI and subsequently compared between the 2 groups. Results: The SLCCT was lower in the AMD group than in the control group (P < 0.05). The HLT was significantly higher in the AMD group than in the control group at the Tparafovea and T-perifovea in the total population (P < 0.05) and in the <= 70-year subgroup (P < 0.05). The CT was higher in the AMD group than in the control group, particularly at the Nperifovea, T-perifovea, and T-parafovea in the <= 70-year subgroup; Interestingly, it was lower in the AMD group than in the control group at the Nparafovea, N-fovea, foveola, and T-fovea in the >70-year subgroup (P < 0.05). Conclusion: This novel AI-based auto-measurement was more accurate, efficient, and detailed than manual measurements. SLCCT thinning was observed in wet AMD; however, CT changes depended on the interaction between HLT compensatory thickening and SLCCT thinning.

引用

页数：7