Effect of metabolic syndrome and its components on the risk and prognosis of cervical cancer: A literature review

被引:1
作者
Kajabwangu, Rogers [1 ]
Izudi, Jonathan [2 ]
Bazira, Joel [3 ]
Ssedyabane, Frank [4 ]
Turanzomwe, Stuart [1 ]
Birungi, Abraham [6 ]
Ngonzi, Joseph [1 ]
Bajunirwe, Francis [2 ]
Randall, Thomas C. [5 ]
机构
[1] Mbarara Univ Sci & Technol, Fac Med, Dept Obstet & Gynaecol, POB 1410, Mbarara, Uganda
[2] Mbarara Univ Sci & Technol, Dept Community Hlth, POB 1410, Mbarara, Uganda
[3] Mbarara Univ Sci & Technol, Dept Med Microbiol, POB 1410, Mbarara, Uganda
[4] Mbarara Univ Sci & Technol, Fac Med, Dept Med Lab Sci, POB 1410, Mbarara, Uganda
[5] Massachusetts Gen Hosp, Boston, MA USA
[6] Mbarara Univ Sci & Technol, Dept Pathol, POB 1410, Mbarara, Uganda
来源
GYNECOLOGIC ONCOLOGY REPORTS | 2024年 / 54卷
基金
美国国家卫生研究院;
关键词
Cervical cancer; Metabolic syndrome; Human papillomavirus; SQUAMOUS-CELL CARCINOMA; LARGE COHORT; ADENOCARCINOMA; OBESITY; MORTALITY; ASSOCIATIONS; RECURRENCE; MECHANISMS; OVERWEIGHT; MANAGEMENT;
D O I
10.1016/j.gore.2024.101438
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Despite the global implementation of preventive strategies against Human Papilloma Virus (HPV) infection, the incidence of invasive cervical cancer rose by nearly 1.3 -fold, from 471,000 annual cases in 2000 to 604,000 cases in 2020. With over 340,000 deaths annually, cervical cancer is the fourth leading cause of cancer mortality in women globally. There is a need to understand other factors besides HPV such as metabolic syndrome (MetS) that potentially influence the onset and progression of cervical cancer. In this narrative review, we describe evidence showing that Metabolic syndrome (MetS) increases the risk for cervical cancer and worsens its prognosis. Combined screening for MetS and cervical cancer has potential to significantly reduce morbidity and mortality in women with cervical cancer.
引用
收藏
页数:5
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