B cells! Don't go the wrong way in this tumor

被引：0
作者：
Pupier, Guilhem [1 ]
Sautes-Fridman, Catherine [1 ]
机构：
[1] Sorbonne Univ, Univ Paris Cite, Ctr Rech Cordeliers, INSERM,Equipe Labellisee Ligue Natl Contre Canc,US, Paris, France
来源：
IMMUNITY | 2024年 / 57卷 / 07期
关键词：
IMMUNITY;
D O I：
10.1016/j.immuni.2024.06.007
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The association of tertiary lymphoid structures (TLSs) with survival and immunotherapy response brought B cells to center stage. In a pan-cancer B cells atlas in Science, Ma et al. show that germinal center reaction generating anti-tumor antibody-secreting cells (ASCs) from B memory cells in mature TLSs co-exist in tumors with extra-follicular reaction generating auto-reactive ASCs from memory B cells in immature TLSs.
引用
收藏
页码：1454 / 1456
页数：3
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