Predictors of mortality in lung cancer patients hospitalized with community-acquired pneumonia

Aim: Lung cancer is a common associated risk factor for pneumonia and increases the severity of pneumonia. In this study, we investigated predictive factors for mortality in patients with lung cancer hospitalized for pneumonia. Material and Methods: In this retrospective study, 821 patients who were hospitalized between 2013-2018 were included. Clinic pathological patient information and laboratory data were obtained from the hospital archive. Evaluation of predictive factors for mortality was performed by logistic regression analysis and the area under the receiver operating characteristic curve (ROC-AUC). Results: The 2 -day mortality rate was 2.4% and the 30 -day mortality rate was 14%. In the multivariate logistic regression analysis, hypotension status (OR=4.18, p=0.004), sodium level (OR=4.30, p=0.007), ALT level (OR=3.83, p=0.027) and calcium level (OR) =6.27, p<0.001) was found to be an independent predictive factor for 2 -day mortality. In 30 -day mortality analysis, hypotension (OR=1.59, p=0.045), albumin level (OR=0.39, p=0.003), LDH level (OR=2.91, p<0.001), sodium level (OR=1.72, p=0.016), eosinophil counts (OR=0.57, p=0.021) and CURB -65 (OR=2.44, p=0.003) score were independent predictive factors. Discussion: Hypotension status, serum sodium level, serum ALT level and serum calcium level for 2 -day mortality and hypotension status, serum albumin level, serum LDH level, serum sodium level, eosinophil counts, and CURB -65 score for 30 -day mortality are potential predictive factors. These predictive factors which can be easily accessible in clinical practice, can be used in the identification of high -risk patients and follow-up of patients.