The Influence of Pharmaceutical Care in Patients with Breast Cancer Receiving Adjuvant Endocrine Therapy

被引：1
作者：
Zhu, Wanhu [1 ]
Chen, Juan [1 ]
Zhao, Xincai [1 ]
Ying, Xuexiang [2 ]
Le, Chun [2 ]
Tang, Fen [2 ]
Qiu, Yao [1 ]
Guo, Cheng [1 ]
Xu, Rong [1 ]
Zhang, Jianping [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 6, Sch Med, Dept Pharm, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 6, Sch Med, Dept Breast Surg, Shanghai, Peoples R China
来源：
AMERICAN JOURNAL OF HEALTH BEHAVIOR | 2024年 / 48卷 / 01期
关键词：
Adjuvant Endocrine Therapy; Breast Cancer; Pharmaceutical Care; Adherence; Medication Beliefs; QUALITY-OF-LIFE; MEDICATION ADHERENCE; HORMONAL-THERAPY; WOMEN; SURVIVORS; PERSISTENCE; TAMOXIFEN; BELIEFS; PROGRAM; COHORT;
D O I：
10.5993/AJHB.48.1.22
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objectives: Our objective was to explore the effect of a pharmaceutical care program on adherence to adjuvant endocrine therapy (AET) in breast cancer patients. Methods: Female breast cancer patients taking AET (N=429) were enrolled in the study; the pharmaceutical care program was implemented and the effect of this intervention was evaluated. The primary outcomes were scores on an 8 -item medication adherence scale Chinese version (MMAS), beliefs about medicines questionnaire specific (BMQ), 5 -level EuroQol 5 dimensions questionnaire (EQ-5D-5L) and a patient satisfaction questionnaire (PSQ-18). Results: We found statistically significant difference in scores on MMAS and BMQ-concern (p < .05) before and after intervention. The MMAS score was 6.12 (+/- 1.21), 7.15 (+/- 0.92) and 7.18 (+/- 0.96) at baseline, 6 months and 12 months, respectively. The BMQ-concern score was 15.64 (+/- 2.14), 12.26 (+/- 2.85), 11.56 (+/- 2.27) at baseline, 6 months and 12 months separately. Conclusion: The pharmaceutical care program significantly improved medication adherence and reduced patients' medication concerns to adjuvant endocrine therapy in Chinese breast cancer patients.
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收藏
页码：231 / 240
页数：10
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