Concise Review: Cell Therapies for Stroke and Traumatic Brain Injury: Targeting Microglia

被引：27

作者：

Savitz, Sean I. ^{[1
]}

Cox, Charles S., Jr. ^{[2
]}

机构：

[1] UT Hlth, Dept Neurol, 6431 Fannin St, Houston, TX 77030 USA

[2] UT Hlth, Dept Pediat Surg, 6431 Fannin St, Houston, TX 77030 USA

来源：

STEM CELLS | 2016年 / 34卷 / 03期

关键词：

Stem cells; Stroke; Microglia; Brain injuries; ACTIVATED MICROGLIAL/MACROPHAGE RESPONSE; MARROW MONONUCLEAR-CELLS; TRANSLOCATOR PROTEIN; 18; KDA; DIFFUSION-TENSOR; INFLAMMATION; NEUROINFLAMMATION; NEURODEGENERATION; DYNAMICS; ATROPHY;

D O I：

10.1002/stem.2253

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

We present a model hypothesis of how several types of cell therapies may target microglia as one of the principal cell types contributing to the inflammatory response after brain injury and discuss how imaging of brain inflammation could potentially be applied to develop biomarkers in patients with stroke and TBI enrolled into stem cell clinical trials.

引用

页码：537 / 542

页数：6

共 35 条

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