Metal-Free ortho C-H Borylation of Thiobenzamides

被引：3
|
作者：
Lv, Jianxing [1 ,2 ]
Liang, Yixuan [1 ,2 ]
Ouyang, Yepeng [1 ,2 ]
Zhang, Hua [1 ,2 ]
机构：
[1] South Cent Minzu Univ, Sch Chem & Mat Sci, Key Lab Catalysis & Energy Mat Chem, Minist Educ, Wuhan 430074, Peoples R China
[2] South Cent Minzu Univ, Sch Chem & Mat Sci, Hubei Key Lab Catalysis & Mat Sci, Wuhan 430074, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 18期
基金：
中国国家自然科学基金;
关键词：
ALPHA-ARYLATION; HETEROAROMATIC-COMPOUNDS; BOND ARYLATION; THIOAMIDES; HYDROXYLATION;
D O I：
10.1021/acs.orglett.4c00691
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A BBr3-mediated S-directed ortho C-H borylation of thiobenzamides was developed. A variety of ortho-borylated thiobenzamides were obtained in moderate to good yields with a wide functional group tolerance under simple and metal-free conditions. This transformation provided a convenient and practical route to important functionalized thiobenzamides.
引用
收藏
页码：3709 / 3714
页数：6
相关论文
共 50 条
  • [1] Metal-free directed C-H borylation
    Xu, Ming-Hua
    CHINESE SCIENCE BULLETIN-CHINESE, 2020, 65 (05): : 331 - 333
  • [2] Metal-Free Stereoconvergent C-H Borylation of Enamides
    Wang, Tianhang
    Wang, Zheng-Jun
    Wang, Minyan
    Wu, Lei
    Fang, Xiaowu
    Liang, Yong
    Lv, Jiahang
    Shi, Zhuangzhi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 62 (44)
  • [3] Metal-free C-H Borylation and Hydroboration of Indoles
    Nad, Pinaki
    Mukherjee, Arup
    ACS OMEGA, 2023, 8 (41): : 37623 - 37640
  • [4] Metal-Free Catalytic Aromatic C-H Borylation
    Zhang, Hua
    Wang, Li
    SYNLETT, 2020, 31 (19) : 1857 - 1861
  • [5] Metal-Free Directed C-H Borylation of Pyrroles
    Wang, Zheng-Jun
    Chen, Xiangyang
    Wu, Lei
    Wong, Jonathan J.
    Liang, Yong
    Zhao, Yue
    Houk, Kendall N.
    Shi, Zhuangzhi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (15) : 8500 - 8504
  • [6] Metal-Free Ortho C-H Borylation of 2-Phenoxypyridines under Mild Conditions
    Niu, Liting
    Yang, Haijun
    Wang, Ruji
    Fu, Hua
    ORGANIC LETTERS, 2012, 14 (10) : 2618 - 2621
  • [7] C-H ACTIVATION Borylation of alkanes goes metal-free
    Boerner, Leigh Krietsch
    CHEMICAL & ENGINEERING NEWS, 2020, 98 (42) : 7 - 7
  • [8] Photoinduced metal-free α-C-H borylation of aliphatic amines
    Guo, Rui
    Shu, Chao
    Zhang, Guozhu
    CHEM, 2022, 8 (11): : 2902 - +
  • [9] Metal-Free Transfer C-H Borylation of Substituted Thiophenes
    Desrosiers, Vincent
    Gaudy, Audrey
    Giroux, Kelly-Anne
    Fontaine, Frederic-Georges
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2023, 649 (9-10):
  • [10] Metal-free catalytic C-H bond activation and borylation of heteroarenes
    Legare, Marc-Andre
    Courtemanche, Marc-Andre
    Rochette, Etienne
    Fontaine, Frederic-Georges
    SCIENCE, 2015, 349 (6247) : 513 - 516
12345